Results 111 to 120 of about 796 (295)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Current status and future trends of computational methods to predict frost formation [PDF]

, 2018
Nowadays, the increasing energy prices and associated environmental concerns lead the refrigeration systems’ developers and manufacturers to develop more energy efficient and sustainable equipment and devices. On the most demanding systems, intense usage
Aguiar, Martim Lima de, Gaspar, Pedro Dinis, Silva, Pedro Dinho da   +2 more
core  

Advances in hybrid icing and frosting protection strategies for optics, lens, and photonics in cold environments using thin film acoustic waves [PDF]

Fogging, icing, or frosting on optical lenses, optics/photonics, windshields, vehicle/ airplane windows, and solar panel surfaces have often shown serious safety concerns with hazardous conditions and impaired sight.
Ong, Hui Ling, Ji, Zhangbin, Haworth, Luke, Guo, Yihao, Moral, Jamie del, Jacob, Stefan, Borras, Ana, Gonzales-Elipe, Augustin R, ZHang, Jikai, ZHou, Jian, McHale, Glen, Fu, Yong-Qing   +11 more
core   +2 more sources

Composite anti-frost heaving pile

, 2023
A.V. Boyarintsev, K.M. Astashkevich, S.V. Lanko   +2 more
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Experimental Investigation on Frost Formation on Cold Surface under Natural Convection Conditions

Zhileng xuebao, 2019
A microscopic visualization method was applied experimentally, where comparative observations of frosting processes were conductedunder the same conditionson bare aluminum and hydrophobic surface with contact angles of 78° and 141°, respectively.
Zhou Shengqi, Liu Yang, Li Weizhong, Qin Yan   +3 more
doaj  

Infusing Silicone and Camellia Seed Oils into Micro-/Nanostructures for Developing Novel Anti-Icing/Frosting Surfaces for Food Freezing Applications. [PDF]

ACS Appl Mater Interfaces, 2023
Zhu Z, Liang H, Sun DW.
europepmc   +1 more source

Inhibition of water vapor condensation by dipropylene glycol droplets on hydrophobic surfaces via vapor sink strategy

Condensation, frosting and icing are natural phenomena, and have been enduring challenges for human society and modern engineering. These phenomena pose a range of issues, from hazardous icy road surfaces, damage to electronic devices due to condensation,
Hu, Jun, Wang, Zhan-Long
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source