Results 171 to 180 of about 39,809 (306)

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

open access: yesAdvanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng   +5 more
wiley   +1 more source

Controlling Photochromism of Donor‐Acceptor Stenhouse Adducts on Micro‐Dot Arrays Beyond Human‐Eyes Resolution for Dynamic Light Encryption

open access: yesAdvanced Science, EarlyView.
This study presents a micro‐dot array strategy for dynamic light encryption, utilizing DASA‐based photochromism with resolution beyond human‐eye capacity. By precisely controlling isomerization kinetics, the method reveals multi‐layered encrypted information under specific light irradiation, enhancing information security and anti‐counterfeiting ...
Hongtao Hu   +10 more
wiley   +1 more source

Evaluation of anti-HBs seropositivity rates in children with familial mediterranean fever. [PDF]

open access: yesEur J Pediatr
Atamyıldız Uçar S   +4 more
europepmc   +1 more source

"Titer of anti-HBs in health professions trainees: prevalence of antibody coverage in a University of Central Italy". [PDF]

open access: yesHum Vaccin Immunother, 2022
Di Giampaolo L   +6 more
europepmc   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

open access: yesAdvanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li   +9 more
wiley   +1 more source

Anti-HBs Immune Complex Levels: A Novel Marker of Hepatitis Flare Following Nucleos(t)ide Analog Withdrawal in HBeAg-negative Chronic Hepatitis B. [PDF]

open access: yesJ Infect Dis
Hume SJ   +22 more
europepmc   +1 more source

Dynamic Regulation of Supramolecular Chirality in an Amphiphilic Dimeric Macrocycle Through Azobenzene‐Based Photoisomerization

open access: yesAdvanced Science, EarlyView.
A stimuli‐responsive supramolecular system has been rationally designed enabling hierarchical control over supramolecular handedness. This hybrid architecture retains orthogonal host‐guest properties and displays unique amphiphilicity‐directed chiral self‐assembly.
Minzan Zuo   +8 more
wiley   +1 more source

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