Results 231 to 240 of about 98,145 (299)
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin +8 more
wiley +1 more source
Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies
MedComm, Volume 7, Issue 5, May 2026.The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He +9 more
wiley +1 more source
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
MedComm, Volume 7, Issue 5, May 2026.Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions
MedComm, Volume 7, Issue 5, May 2026.We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu +8 more
wiley +1 more source
Assessment of central blood volume in cirrhosis by radionuclide angiography [PDF]
, 1994 Bendtsen, Flemming +10 more
core
Respirology Case Reports, Volume 14, Issue 5, May 2026.We present a case of hepatoid adenocarcinoma in the lung which was initially misdiagnosed as pneumonia and rapidly progressed to widespread metastatic disease. This case emphasises the diagnostic difficulty, radiological and histopathologic characteristics, and aggressive clinical behaviour of this rare tumour and underscores the need for early ...
Rami Khader +7 more
wiley +1 more source
Tenofovir, Interferon Pathways, and Mucosal Immunity: Implications for People Living With HIV
American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.ABSTRACT Background Antiretroviral therapy (ART) suppresses HIV replication and protects people living with HIV (PLWH) from progressing to AIDS. However, despite ART, many PLWH experience chronic immune activation, which contributes to premature aging and non‐AIDS‐related comorbidities. One reason for this chronic immune activation (CIA) is HIV and its
Florian Hladik +5 more
wiley +1 more source
Brain Pathology, Volume 36, Issue 3, May 2026.Despite effective ART, neurocognitive impairment persists in people with HIV. Brains from PWH present exacerbated microgliosis and formation of microglial nodules that are actively engaged in neuronal phagocytosis, resulting in neuronal injury and dendritic loss.
Roberta S. Dos Reis +12 more
wiley +1 more source
Considerations for the Use of AAV‐based Gene Therapy in HIV‐Positive Individuals With Haemophilia
Haemophilia, Volume 32, Issue 3, Page 584-592, May/June 2026.ABSTRACT Introduction There is a high prevalence of human immunodeficiency virus (HIV) infection among the haemophilia community due to treatment in the 1970s and 1980s with contaminated clotting factor. Lifelong treatment regimens for haemophilia and HIV are burdensome alone and pose a particular challenge for individuals living with both conditions ...
Jürgen K. Rockstroh +5 more
wiley +1 more source