Results 201 to 210 of about 312,758 (261)

Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells. [PDF]

open access: yesNoncoding RNA
Schlösser V   +11 more
europepmc   +1 more source

CXCR4 Is a Potential Target for Anti-HIV Gene Therapy. [PDF]

open access: yesInt J Mol Sci
Prokopovich AK   +3 more
europepmc   +1 more source
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Anti-HIV ribozymes

Molecular Biotechnology, 1997
HIV is an RNA virus that replicates intracellularly through various RNA intermediates. Several of these can be targeted by ribozymes (catalytic RNA molecules), and a number of investigators, including this group, have demonstrated the ability of ribozymes to suppress HIV replication in this way.
L Q, Sun   +3 more
openaire   +5 more sources

Anti-HIV Cyclotides

Current Protein & Peptide Science, 2004
The cyclotides are a recently discovered, structurally unique family of bioactive plant peptides. Their discovery spawned a series of structural analyses, synthetic efforts, and studies to define the biosynthesis and biological properties of these novel peptide metabolites.
Kirk R, Gustafson   +2 more
openaire   +2 more sources

Pharmacogenetics of Anti-HIV Drugs

Annual Review of Pharmacology and Toxicology, 2008
Pharmacogenetics holds promise in HIV treatment because of the complexity and potential toxicity of multidrug therapies that are prescribed for long periods. Thus far, few candidate genes have been examined for a limited number of allelic variants, but a number of confirmed associations have already emerged.
Telenti A, Zanger UM
openaire   +3 more sources

Emerging anti-HIV drugs

Expert Opinion on Emerging Drugs, 2005
There are now exactly 20 anti-HIV drugs licenced (approved) for clinical use, and > 30 anti-HIV compounds under (pre)clinical development. The licensed anti-HIV drugs fall into five categories: nucleoside reverse transcriptase inhibitors (NRTIs: zidovudine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine); nucleotide reverse ...
openaire   +2 more sources

Towards anti-HIV vaccines

Vaccine, 1988
There is a great deal of experience on the development and testing of antiviral vaccines but, in the case of HIV, it will be necessary to analyse carefully our understanding of the biology of the organism, the natural history and pathology of the disease (in particular immunity or resistance to infection or clinical symptoms), the possible sources of ...
openaire   +2 more sources

Model-based anti-HIV therapy

2008
Modern combination drug therapy has substantially improved the clinical management of HIV-1 infection. Still, the emergence of drug-resistant variants eventually leads to therapy failure in most patients. The selection of an optimal follow-up regimen is complicated by an ever-increasing range of possible drug combinations.
openaire   +3 more sources

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