Results 141 to 150 of about 2,671,914 (293)

Impact of immunoglobulin preparations on anti-HLA antibody specificity analysis

Laboratory Medicine
Abstract Background Donor-specific antibodies (DSAs) targeting human leukocyte antigens (HLAs) substantially reduce the longevity of transplanted organs. Desensitization of DSA-positive renal transplant recipients is achieved through intravenous administration of immunoglobulin (IVIg).
Rie Nakagawa, Hideaki Matsuura, Hayato Kojima, Yuko Abe, Ayuna Yamada, Hiroki Doi, Yasuo Miura   +6 more
openaire   +2 more sources

A Computed Tomography Radiomics Approach for Assessing the T Cell‐Inflamed Gene Expression Profile in Hepatocellular Carcinoma and Its Association With Immunotherapy Response

Health Care Science, EarlyView.
The T cell‐inflamed gene expression profile (GEP) provides a biomarker for immunotherapy response across various cancers. We established a CT‐based radiomics model to predict the T cell‐inflamed GEP and immunotherapy response in hepatocellular carcinoma (HCC).
Mimi Tang, Kaiyu Sun, Dasheng Wu, Yujian Zou, Jian Zhou, Bin Li, Huanjing Hu, Zhenpeng Peng, Jifei Wang, Bingsheng Huang, Shi‐Ting Feng, Shuling Chen   +11 more
wiley   +1 more source

Everolimus plus reduced calcineurin inhibitor prevents <i>de novo</i> anti-HLA antibodies and humoral rejection in kidney transplant recipients: 12-month results from the ATHENA study. [PDF]

Front Transplant, 2023
Arns W, Philippe A, Ditt V, Hauser IA, Thaiss F, Sommerer C, Suwelack B, Dragun D, Hillen J, Schiedel C, Elsässer A, Nashan B.   +11 more
europepmc   +1 more source

Shared and Distinguishing Features of Late‐Onset Rheumatic Diseases Fulfilling Polymyalgia Rheumatica Classification Criteria

Arthritis &Rheumatology, EarlyView.
Kerem Abacar, Ala Altaie, Andrew Barr, Sarah L. Mackie, Kulveer Mankia, Dennis McGonagle   +5 more
wiley   +1 more source

Post-transplant donor-specific anti-HLA antibodies with a higher mean fluorescence intensity are associated with graft fibrosis in pediatric living donor liver transplantation. [PDF]

Front Pediatr, 2023
Goto R, Fukasaku Y, Ganchiku Y, Kawamura N, Watanabe M, Ota T, Hatanaka KC, Suzuki T, Shimamura T, Taketomi A.   +9 more
europepmc   +1 more source

Association of HLA Mismatches and Histology Suggestive of Antibody-Mediated Injury in the Absence of Donor-Specific Anti-HLA Antibodies. [PDF]

Clin J Am Soc Nephrol, 2022
Senev A, Lerut E, Coemans M, Callemeyn J, Copley HC, Claas F, Koshy P, Kosmoliaptsis V, Kuypers D, Sprangers B, Van Craenenbroeck A, Van Loon E, Van Sandt V, Emonds MP, Naesens M.   +14 more
europepmc   +1 more source

Human HLA specific antibodies crossreact with swine leucocyte antigens. [PDF]

, 2018
Background: Organs transplanted between discordant species such as pig-to-primate, undergo hyperacute rejection due to the presence of natural xenogenic antibodies. Hyperacute rejection xenograft rejection can now be controlled by various approaches, but
Van Dam, Mieke Gerharda.
core  

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

The allograft injury marker CXCL9 determines prognosis of anti-HLA antibodies after lung transplantation. [PDF]

Am J Transplant, 2022
Shino MY, Zhang Q, Li N, Derhovanessian A, Ramsey A, Saggar R, Britton IN, Amubieya OO, Lari SM, Hickey M, Reed EF, Noble PW, Stripp BR, Fishbein GA, Lynch JP, Ardehali A, Sayah DM, Weigt SS, Belperio JA.   +18 more
europepmc   +1 more source