Results 181 to 190 of about 2,671,914 (293)

Early-onset de novo donor-specific anti-HLA antibodies may contribute to poor graft function following haploidentical transplantation for myelodysplastic syndrome: a rare case presentation. [PDF]

Ther Adv Hematol
Huang X, Wu X, Wang S, Xu Y, Mei C, Du F, Ren Y, Jin J, Tong H, Qian J.   +9 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Engraftment outcome of patients with anti-HLA antibodies in HLA-mismatched peripheral blood stem cell transplantation. [PDF]

Int J Hematol
Hagino T, Ikegame K, Tanaka H, Kanda Y, Kaida K, Fukuda T, Kondo Y, Sato M, Doki N, Nakamae H, Matsuoka KI, Mori Y, Sano H, Eto T, Kawakita T, Hashii Y, Ichinohe T, Atsuta Y, Kanda J, HLA Working Group of Japanese Society for Transplantation, Cellular Therapy.   +20 more
europepmc   +1 more source

Donor specific anti-HLA antibodies and cardiac allograft vasculopathy: A prospective study using highly automated 3-D optical coherence tomography analysis. [PDF]

Transpl Immunol, 2021
Pazdernik M, Bedanova H, Chen Z, Kautzner J, Melenovsky V, Malek I, Slavcev A, Bartonova M, Karmazin V, Eckhardt T, Tomasek A, Ozabalova E, Kovarnik T, Wohlfahrt P, Sonka M.   +14 more
europepmc   +1 more source

Enhanced Recovery After Surgery in Simultaneous Pancreas–Kidney Transplantation: A Retrospective Cohort Analysis of Perioperative Outcomes

Organ Medicine, EarlyView.
ABSTRACT Background While simultaneous pancreas–kidney transplantation (SPK) is an established therapeutic intervention for patients with end‐stage renal disease and diabetes, it has been associated with prolonged recovery periods and high complication rates.
Rongxin Chen, Luhao Liu, Jialin Wu, Zhuangqiang Fang, Guanghui Li, Zheng Chen   +5 more
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

ASTCT Consensus Recommendations on Testing and Treatment of Patients with Donor-specific Anti-HLA Antibodies. [PDF]

Transplant Cell Ther
Kongtim P, Vittayawacharin P, Zou J, Srour S, Shaffer B, Shapiro RM, Varma A, McGuirk J, Dholaria BR, McCurdy SR, DeZern AE, Bejanyan N, Bashey A, Furst S, Castagna L, Mariotti J, Ruggeri A, Bailen R, Teshima T, Xiao-Jun H, Bonfim C, Aung F, Cao K, Carpenter PA, Hamadani M, Askar M, Fernandez-Vina M, Girnita A, Ciurea SO.   +28 more
europepmc   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Increasing donor kidney age significantly aggravates the negative effect of pretransplant donor-specific anti-HLA antibodies on kidney graft survival. [PDF]

Front Immunol
Betjes MGH, Kal-van Gestel JA, Roelen D, Kho MML, Heidt S, de Weerd AE, van de Wetering J.   +6 more
europepmc   +1 more source