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Advanced Science, EarlyView.This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
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Management of multiple drug hypersensitivity in a child with very severe aplastic anemia: a case report and therapeutic challenge. [PDF]
Front PediatrChen M +8 more
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Perioperative Antibiotic Prophylaxis in Burn Patients: Protocol for a Systematic Review. [PDF]
Acta Anaesthesiol ScandChristensen GBB +9 more
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Enterococcus endocarditis in an infant with congenital renal duplex anomaly: A case report. [PDF]
Forensic Sci Med PatholRao E, Annavarapu S.
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Dual Infection with dengue virus and infective endocarditis leading to brain abscess, multiorgan infarctions, and horner syndrome: a case report with literature review. [PDF]
BMC Cardiovasc DisordSulaiman D, Moqbil S, Moqbel O.
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Benzothiazole Derivatives as Potential Anti-Infective Agents
Current Topics in Medicinal Chemistry, 2016Severity of microbial infections and escalating resistance towards antibiotics has created a deep necessity for discovery of novel anti-infective agents. Heterocyclic chemistry of benzothiazole has become one of the most prolific areas in the field of drug discovery and development that has attracted great attention in recent time due to its increasing
Meenakshi Pathak +2 more
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