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Infections, Anti-infective Agents, and Risk of Deliberate Self-harm and Suicide in a Young Cohort: A Nationwide Study [PDF]
Biological Psychiatry, 2019 BACKGROUND: Evidence links infections to mental disorders and suicidal behavior. However, knowledge is sparse regarding less severe infections, anti-infective treatment, and deliberate self-harm.
Ole Kohler-Forsberg +2 more
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Cheminformatics in Anti-Infective Agents Discovery
Mini-Reviews in Medicinal Chemistry, 2007The existing chemical data such as those created by high throughput screening (HTS), structure-activity relationship (SAR) studies are converted into information as a result of storage and registration. Accessibility, manipulation, and data mining of such information make up the knowledge for drug development.
S, Sardari, M, Dezfulian
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Anti-infective agents and hepatic disease
Medical Clinics of North America, 1995Numerous factors such as changes in plasma protein binding, tissue binding, hepatic blood flow, hepatic metabolism, and distribution may occur in hepatic disease. The impact of these physiologic changes on pharmacokinetic and pharmacodynamic parameters of anti-infective agents is likely to be clinically significant. Unfortunately, these issues have not
S J, Tschida, K, Vance-Bryan, D E, Zaske
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1995
Chemotherapeutic agents are intended to eliminate foreign organisms or abnormal cells from healthy tissues of the patient. An essential property of all chemotherapeutic drugs is selective toxicity; deleterious actions directed against the target cells without comparable effects on the tissue of the host.
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Chemotherapeutic agents are intended to eliminate foreign organisms or abnormal cells from healthy tissues of the patient. An essential property of all chemotherapeutic drugs is selective toxicity; deleterious actions directed against the target cells without comparable effects on the tissue of the host.
openaire +1 more source
1984
In the 50-year period since Fleming made his monumental discovery of penicillin, a vast array of anti-infective agents have been developed to combat the plethora of infectious microorganisms plaguing mankind. While once the ophthalmologist had only penicillin to resort to when faced with ocular infection, his choice now includes myriads of antibiotics.
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In the 50-year period since Fleming made his monumental discovery of penicillin, a vast array of anti-infective agents have been developed to combat the plethora of infectious microorganisms plaguing mankind. While once the ophthalmologist had only penicillin to resort to when faced with ocular infection, his choice now includes myriads of antibiotics.
openaire +1 more source
Discovery of novel anti-infective agents
Academic and other non-profit institutions have a long-term vision to improve human health where commercial interests can be limited for profit organizations. Medicinal chemistry to these diseases with no commercial benefit needs is well suited in the academic environment and this chapter outlines some work conducted at Calibr-Skaggs around antibiotic ...openaire +2 more sources
Medicinal/Pharmaceutical Chemistry and Engineering of Anti-infective Agents
Anti-Infective Agents, 2021Niranjan Koirala
exaly