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Anti-Inflammation Activity of Flavones and Their Structure–Activity Relationship
Journal of Agricultural and Food Chemistry, 2021Flavones are an important class of bioactive constituents in foods, and their structural diversity enables them to interact with different targets. In particular, flavones are known for their anti-inflammatory activity. Herein, we summarized commonly applied in vitro, in vivo, and clinical models in testing anti-inflammatory activity of flavones.
Xiang Wang +5 more
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Anti-inflammation furanoditerpenoids from Caesalpinia minax Hance
Phytochemistry, 2015Cassane skeletons are rare in nature, but often possess valuable medicinal properties. A furanoditerpenoid with an unusual A-seco-rearranged cassane skeleton, neocaesalminin A, and five furanoditerpenoids were isolated from seeds of Caesalpinia minax Hance, along with six known cassane derivatives, 7-O-acetyl-bonducellpin C, caesalmin F, caesalmin C, ζ-
Dong, Ruijuan +6 more
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Effect of food on kinetics of the nonsteroidal anti‐inflammative, alclofenac
Clinical Pharmacology & Therapeutics, 1978Two clinical studies were conducted on the kinetics of alclofenac in healthy adult male volunteers. The first involved 32 subjects, each of whom received a single oral 500‐mg dose of alclofenac as an aqueous suspension to study the oral pharmacokinetics of the drug.
L T, Sennello, R C, Sonders, N, Friedman
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Anti-inflammation and Antifibroblastic Actions of Interleukin-1 Blockers
Journal of Ocular Pharmacology and Therapeutics, 1998Interleukin-1 (IL-1) blockers, CK 127 and CK 129, were found to inhibit IL-1-induced posterior uveitis very effectively at 3-10 mg/kg i.p. and were more potent than prednisolone which required at least 20 mg/kg i.p. to achieve the same level of anti-uveitis action.
G C, Chiou +3 more
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Intracellular coassembly boosts the anti-inflammation capacity of dexamethasone
Nanoscale, 2017An intracellular coassembly strategy was developed to boost the anti-inflammation capacity of dexamethasone.
Wei Tang +4 more
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