Results 271 to 280 of about 1,249,360 (312)

Synthesis of sorbicillinoid analogues with anti-inflammation activities

Bioorganic & Medicinal Chemistry, 2022
Recently, we demonstrated potential anti-inflammatory effects of sorbicillinoids isolated from marine fungi. Here, we report the synthesis of a series of new sorbicillinoid analogues and assessed their anti-inflammatory activities. Our results reveal that side chain substitution with (E)-2-butenoyl, (E)-3-(4-fluorophenyl)-2-propenoyl, and (E)-3-(3,4,5 ...
Meng, Zhang, Fangfang, Wang, Wenjuan, Ding, Zhipeng, Xu, Xiaosan, Li, Danmei, Tian, Youwei, Zhang, Jinshan, Tang   +7 more
openaire   +2 more sources

An Anti-anti-inflammation Concept

Nature, 1965
THE induction of the inflammatory process has been ascribed to the local release of cellular agents such as histamine, serotonin, or other excitants. Such excitants have been considered as inflammatory agents or, more recently, as mediators of inflammation.
D E, Holtkamp, A C, Levy
openaire   +2 more sources

Anti-Inflammation activity ofActinidia polygama

Archives of Pharmacal Research, 2003
The fruit of Actinidia polygama (AP) has long been used as a folk medicine in Korea for treating pain, rheumatic arthritis and inflammation. The present investigation was carried out to determine the in vivo and in vitro anti-inflammatory activity of AP using several animal models of inflammation.
Yoo Kyung, Kim, Hyo Joo, Kang, Kyung Tae, Lee, Jin Gyu, Choi, Sung Hyun, Chung   +4 more
openaire   +2 more sources

Anti-Inflammation Activity of Flavones and Their Structure–Activity Relationship

Journal of Agricultural and Food Chemistry, 2021
Flavones are an important class of bioactive constituents in foods, and their structural diversity enables them to interact with different targets. In particular, flavones are known for their anti-inflammatory activity. Herein, we summarized commonly applied in vitro, in vivo, and clinical models in testing anti-inflammatory activity of flavones.
Xiang Wang, Yujia Cao, Siyu Chen, Jiachen Lin, Jinsong Bian, Dejian Huang   +5 more
openaire   +2 more sources

Toxins in anti-nociception and anti-inflammation

Toxicon, 2004
The use of toxins as novel molecular probes to study the structure-function relationship of ion-channels and receptors as well as potential therapeutics in the treatment of wide variety of diseases is well documented. The high specificity and selectivity of these toxins have attracted a great deal of interest as candidates for drug development.
Wudayagiri, Rajendra, Arunmozhiarasi, Armugam, Kandiah, Jeyaseelan   +2 more
openaire   +2 more sources

Anti-inflammation biomaterial platforms for chronic wound healing

Biomaterials Science, 2021
Chronic wound has developed into one of the most serious health problems worldwide; the rate-limiting stage of chronic wound healing is the inflammation stage; we reviewed the advances and impact of various anti-inflammatory biomaterial platforms.
Zejun Xu, Biao Liang, Junzhang Tian, Jun Wu   +3 more
openaire   +2 more sources

Biphasic dose response in the anti-inflammation experiment of PBM

Lasers in Medical Science, 2023
Non-invasive laser irradiation can induce photobiomodulation (PBM) effects in cells and tissues, which can help reduce inflammation and pain in several clinical scenarios. The purpose of this study is to review the current literature to verify whether PBM can produce dose effects in anti-inflammatory experiments by summarizing the clinical and ...
Fang, Nie, Shaolong, Hao, Yu, Ji, Yan, Zhang, Hao, Sun, Melissa, Will, Wei, Han, YuChuan, Ding   +7 more
openaire   +2 more sources

Effective constituents in Xiexin Decoction for anti-inflammation

Journal of Ethnopharmacology, 2009
To ascertain the effective constituents in Xiexin Decoction for anti-inflammation and the interactions of these constituents at the pharmacodynamic level.Rats were administered oral Xiexin Decoction 1h before intraperitoneal lipopolysaccharide. Nitric oxide production and Xiexin Decoction constituents in venous serum samples were quantified and the ...
Bing-Liang, Ma, Yue-Ming, Ma, Dong-Ming, Yan, Hui, Zhou, Rong, Shi, Tian-Ming, Wang, Yang, Yang, Chang-Hong, Wang, Ning, Zhang   +8 more
openaire   +2 more sources

Bilirubin Nanoparticles as a Nanomedicine for Anti‐inflammation Therapy

Angewandte Chemie International Edition, 2016
AbstractDespite the high potency of bilirubin as an endogenous anti‐inflammatory compound, its clinical translation has been hampered because of its insolubility in water. Bilirubin‐based nanoparticles that may overcome this critical issue are presented.
Yonghyun, Lee, Hyungjun, Kim, Sukmo, Kang, Jinju, Lee, Jinho, Park, Sangyong, Jon   +5 more
openaire   +2 more sources

P2X7 is involved in the anti-inflammation effects of levobupivacaine

Journal of Surgical Research, 2015
We sough to elucidate whether purinergic P2X7 receptor is actively involved in the effects of levobupivacaine on inhibiting microglia activation.Microglia were treated with lipopolysaccharide (LPS, 50 ng/mL), LPS plus levobupivacaine (50 μM), or LPS plus levobupivacaine plus the P2X7 receptor agonist Bz-ATP (100 μM) and denoted as the LPS, LPS + Levo ...
Ya-Hsien, Huang, Jiin-Cherng, Yen, Jie-Jen, Lee, Jyh-Fei, Liao, Wen-Jinn, Liaw, Chun-Jen, Huang   +5 more
openaire   +2 more sources