POS0907 EFFECT OF UPADACITINIB ON REDUCING PAIN IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS AND INADEQUATE RESPONSE TO NONSTEROIDAL ANTI-INFLAMMATORY DRUGS [PDF]
, 2021 Atul Deodhar +10 more
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FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
A mixture of Iranian probiotics had anti-inflammatory and antioxidative effects in oxidative injuries induced by cadmium in liver and blood parameters [PDF]
, 2022 Arezu kohan, Zahra Keshtmand
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Targeting cancer-promoting inflammation — have anti-inflammatory therapies come of age?
Nature Reviews Clinical Oncology, 2021 J. Hou, M. Karin, Beicheng Sun
semanticscholar +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis [PDF]
, 2004 Olivier Gasser, Jürg A. Schifferli
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FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Complementary Medicine Journal of Faculty of Nursing and Midwifery, 2019 Introduction: There are some reports in traditional medicine concerning the anti-inflammatory, anti-nociceptive and anti-pyretic effects of Trifolium pretense (red clover).
Parandin R
doaj
Trogocytosis in CAR immune cell therapy: a key mechanism of tumor immune escape
Cell Communication and SignalingImmune cell therapy based on chimeric antigen receptor (CAR) technology platform has been greatly developed. The types of CAR immune cell therapy have expanded from T cells to innate immune cells such as NK cells and macrophages, and the diseases treated
Yizhao Chen +6 more
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Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model
Frontiers in Bioengineering and BiotechnologyIntroductionTo investigate the metabolism and distribution of iPSC‐MSCs in the joint cavity of rats with knee osteoarthritis (KOA).MethodsThe iPSC‐MSCs labeled with the Antares2 luciferase gene were injected into the knee joints of rats, and then the ...
Xiaoyang Yuan +13 more
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