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Anti-inflammatory Action of Green Tea
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2016Green tea has been shown to have beneficial effects against a variety of diseases such as cancer, obesity, diabetes, cardiovascular disease, and neurodegenerative diseases. Through cellular, animal, and human experiments, green tea and its major component, epigallocatechin-3-gallate (EGCG) have been demonstrated to have anti-inflammatory effects.
Tomokazu, Ohishi +4 more
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The anti-inflammatory action of nepitrin, a flavonoid
Agents and Actions, 1982The anti-inflammatory efficacy of nepitrin (5,3',4'-trihydroxy-6-methoxy flavone), a flavonoid, was investigated in both acute and chronic models of inflammation in rats. Nepitrin was found to possess significant anti-inflammatory activity in the exudative and proliferative phases of inflammation.
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An overview of glucocorticoid anti-inflammatory actions
European Journal of Clinical Pharmacology, 1993Glucocorticoids (GC) exert a variety of important anti-inflammatory actions. We have studied their effects in allergic inflammation and believe that their anti-allergic effects reflect their anti-inflammatory activities in general. These effects include inhibition of cytokine and other mediator secretion, inhibition of leucocyte priming in eosinophils ...
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The Anti-inflammatory Action of Glucocorticoid Hormones
2002Inflammation and immune response are elaborate reactions of mammalian organisms to environmental attacks. As in any stimulated process, the existence of brakes that limit the response, is decisive for survival of the organism. Imagine a bacterial infection: the uncontrolled response, in form of cytokine release by macrophages, e.g.
Herrlich, P., Göttlicher, M.
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ON THE ANTI-INFLAMMATORY ACTION OF AMINOACETONITRILE (AAN)
Canadian Journal of Biochemistry and Physiology, 1957Experiments on adrenalectomized rats maintained on small doses of cortisol acetate and desoxycorticosterone acetate indicate that aminoacetonitrile markedly inhibits the production of inflammatory exudate in the "granuloma pouch" test. It is concluded that this antiphlogistic effect is an inherent property of the lathyrogenic aminonitrile and not ...
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Mechanism of Action of Anti-Inflammatory Drugs
Scandinavian Journal of Rheumatology, 1996Cyclooxygenase (COX) is the pivotal enzyme in prostaglandin biosynthesis. It exists in two isoforms, constitutive COX-1 (responsible for physiological functions) and inducible COX-2 (involved in inflammation). Inhibition of COX explains both the therapeutic effects (inhibition of COX-2) and side effects (inhibition of COX-1) of non-steroidal anti ...
J R, Vane, R M, Botting
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Molecular mechanisms of anti‐inflammatory action of glucocorticoids
BioEssays, 1996AbstractGlucocorticoid hormones are effective in controlling inflammation, but the mechanisms that confer this action are largely unknown. Recent advances in this field have shown that both positive and negative regulation of gene expression are necessary for this process. The genes whose activity are modulated in the anti‐inflammatory process code for
Cato, A. C. B., Wade, E.
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Anti-Inflammatory Cytokines: Expression and Action in the Brain
Neuroimmunomodulation, 2001Transforming growth factor-β<sub>1</sub> (TGF-β<sub>1</sub>) and interleukin (IL)-10 gene expression is equivocal in normal brain and upregulated in over a dozen central and peripheral diseases/disorders. The patterns of specific expression of cytokines differ in these diseases.
L, Vitkovic, S, Maeda, E, Sternberg
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The Mechanism of Action of Anti-Inflammatory Drugs
2000The forefather of aspirin, salicylic acid, is a constituent of several plants long used as medicaments. About 3500 years ago, the Ebers papyrus recommended the application of a decoction of dried leaves of myrtle to the abdomen and back to expel rheumatic pains from the womb.
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International archives of allergy and applied immunology, 1991
Tioxamast is an antiallergic drug that inhibits anaphylaxis in various models in rats, and it inhibits the release and synthesis of certain mediators of inflammation [see Tarayre et al., this issue]. Here we report that the drug also has an anti-inflammatory effect in vivo in various nonimmunological models in rats.
J P, Tarayre +9 more
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Tioxamast is an antiallergic drug that inhibits anaphylaxis in various models in rats, and it inhibits the release and synthesis of certain mediators of inflammation [see Tarayre et al., this issue]. Here we report that the drug also has an anti-inflammatory effect in vivo in various nonimmunological models in rats.
J P, Tarayre +9 more
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