Results 251 to 260 of about 7,096,396 (300)

Anti-Inflammatory Action of Methimazole

Pharmacology, 2008
The anti-inflammatory activity of 1-methylimidazole-2-thiol (methimazole), the most widely used antithyroid drug, was investigated. Methimazole had a marked inhibitory action on prostaglandin H synthase (IC₅₀ = 10 µmol/l), inhibiting the peroxidase (IC₅₀ = 330 µmol/l), although the cyclo-oxygenase was ...
J F, Lagorce, T, Moulard, A, Rousseau, F, Comby, J, Buxeraud, C, Raby   +5 more
openaire   +2 more sources

Ocular Anti-Inflammatory Actions of Matrine

Journal of Ocular Pharmacology and Therapeutics, 1987
Matrine is an alkaloid isolated from the root of Sophora subprostrata (Leguminosae) which has been used as a Chinese medicine for the treatment of inflammation. Instillation of 50 microliter of 1% matrine showed significant inhibition of ocular inflammation induced by lens proteins. Unlike corticosteroids, matrine did not facilitate the IOP recovery in
C Y, Chuang, J G, Xiao, G C, Chiou
openaire   +2 more sources

Anti-inflammatory action of sulfated polysaccharides

Biochemical Pharmacology, 1969
Abstract A number of sulfated polymers: pentosan polysulfate, polyvinyl sulfate, polyethylene sulfonate, cellulose sulfate, dextran sulfate, sulfate amylopectin, in the same way as carragenin, degraded carragenin and dextran, produce edema in the rat's paw by local injection, to release kinins from fresh guinea pig and rat's plasma (in vitro) and to ...
M, Rocha e Silva, R Q, Cavalcanti, M L, Reis   +2 more
openaire   +2 more sources

Mechanisms of action of anti-inflammatory drugs

General Pharmacology: The Vascular System, 1976
Abstract 1. 1. Current and older hypotheses on the mode of action of nonsteroid anti-inflammatory drugs (NSAID) are reviewed. 2. 2. It is shown that even the most convincing concept that NSAID exert their action by inhibiting the biosynthesis of prostaglandins (PG's) leaves several questions unanswered. 3. 3.
K, Brune, M, Glatt, P, Graf
openaire   +2 more sources

Anti-Inflammatory Actions of Intravenous Immunoglobulin

Annual Review of Immunology, 2008
The remarkable success story of the therapeutic application of pooled immunoglobulin G (IgG) preparations from thousands of donors, the so-called intravenous IgG (IVIG) therapy, to patients with a variety of hematological and immunological disorders began more than half a century ago.
Falk, Nimmerjahn, Jeffrey V, Ravetch
openaire   +2 more sources

Anti-inflammatory drugs and their mechanism of action

Inflammation Research, 1998
Nonsteroidal anti-inflammatory drugs (NSAIDs) produce their therapeutic activities through inhibition of cyclooxygenase (COX), the enzyme that makes prostaglandins (PGs). They share, to a greater or lesser degree, the same side effects, including gastric and renal toxicity. Recent research has shown that there are at least two COX isoenzymes.
J R, Vane, R M, Botting
openaire   +2 more sources

Anti-Inflammatory Action of Isorhamnetin

Inflammation, 2014
Dear Editor, A recent paper from Kynhwa Seo and colleagues in the latest issue of this journal reported that isorhamnetin, n ame l y ( 3 , 5 , 7 t r i h y d r o x y 2 ( 4 h y d r o x y 3 methoxyphenyl)chromen-4-one or quercetin-3methylether), a 3′-O-methylated metabolite of quercetin, reduced inducible nitric oxide synthase (iNOS) expression and NO ...
openaire   +2 more sources

The Anti‐Inflammatory Actions of Antithrombin – A Review

Acta Medica Austriaca, 2002
Summary: Leukocyte–endothelial cell interaction and microvascular perfusion failure are characteristic deteriorations of the microcirculation in endotoxaemia and are known to play a crucial role in the development of septic multiple organ dysfunction. Recent studies have indicated that antithrombin III treatment is capable of significantly ameliorating
Ch J, Wiedermann, J, Römisch
openaire   +2 more sources

Anti-inflammatory actions of boswellic acids

Phytomedicine, 1996
Boswellic acids (BA) demonstrated dose-related anti-inflammatory activity (AIA) in acute tests of carrageenan-, histamine- and dextran-induced edema in rats and mice. It elicited inhibitory action on vascular permeability in mice induced by acetic acid.
G B, Singh, S, Singh, S, Bani
openaire   +2 more sources

MECHANISM OF ANTI-INFLAMMATORY ACTION OF GLUCOCORTICOSTEROIDS

The Lancet, 1977
Glucocorticosteroids react with blood monocytes and tissue macrophages to produce a peptide factor which stimulates the random migration of polymorphs in vitro in the capillary-tube migration system. An identical effect on polymorph migration is produced by colchicine and vinblastine, drugs which inhibit the assembly of the cytoplasmic microtubules on ...
openaire   +2 more sources