Results 271 to 280 of about 901,503 (311)

Mechanisms of action of anti-inflammatory drugs

General Pharmacology: The Vascular System, 1976
Abstract 1. 1. Current and older hypotheses on the mode of action of nonsteroid anti-inflammatory drugs (NSAID) are reviewed. 2. 2. It is shown that even the most convincing concept that NSAID exert their action by inhibiting the biosynthesis of prostaglandins (PG's) leaves several questions unanswered. 3. 3.
K, Brune, M, Glatt, P, Graf
openaire   +2 more sources

Anti-inflammatory actions of steroids: molecular mechanisms

Trends in Pharmacological Sciences, 1993
Glucocorticosteroids are highly effective in controlling inflammation and the molecular mechanisms involved are now becoming clear. Activation of glucocorticoid receptors results in increased or decreased transcription of a number of genes involved in the inflammatory process.
Peter J. Barnes, Ian Adcock, Michael Spedding, Paul M. Vanhoutte   +3 more
openaire   +2 more sources

Anti-inflammatory actions of lipoxins

Expert Opinion on Therapeutic Patents, 2007
Efforts to understand and harness the potent anti-inflammatory and immunomodulating properties of the endogenous lipid mediators lipoxin A4 (LXA4), lipoxin B4 (LXB4) and the aspirin-triggered lipoxins, have resulted in a number of patent applications by both academic research groups and pharmaceutical companies.
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Anti-inflammatory Actions of Glucocorticoids: Molecular Mechanisms

Clinical Science, 1998
1. Glucocorticoids are widely used for the suppression of inflammation in chronic inflammatory diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease and autoimmune diseases, all of which are associated with increased expression of inflammatory genes.
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The Anti-inflammatory Action of Glucocorticoid Hormones

2002
Inflammation and immune response are elaborate reactions of mammalian organisms to environmental attacks. As in any stimulated process, the existence of brakes that limit the response, is decisive for survival of the organism. Imagine a bacterial infection: the uncontrolled response, in form of cytokine release by macrophages, e.g.
Herrlich, P., Göttlicher, M.
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An overview of glucocorticoid anti-inflammatory actions

European Journal of Clinical Pharmacology, 1993
Glucocorticoids (GC) exert a variety of important anti-inflammatory actions. We have studied their effects in allergic inflammation and believe that their anti-allergic effects reflect their anti-inflammatory activities in general. These effects include inhibition of cytokine and other mediator secretion, inhibition of leucocyte priming in eosinophils ...
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Antiallergic and anti-inflammatory action of tioxamast in rats. II. Anti-inflammatory action in vivo.

International archives of allergy and applied immunology, 1991
Tioxamast is an antiallergic drug that inhibits anaphylaxis in various models in rats, and it inhibits the release and synthesis of certain mediators of inflammation [see Tarayre et al., this issue]. Here we report that the drug also has an anti-inflammatory effect in vivo in various nonimmunological models in rats.
J P, Tarayre, M, Aliaga, M, Barbara, N, Tisseyre, V, Caillol, A, Delhon, F, Bruniquel, X, N'Guyen, L, Puech, J, Tisné-Versailles   +9 more
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[Anti-inflammatory action of PPARs].

Nihon rinsho. Japanese journal of clinical medicine, 2005
The PPARs transduce a wide variety of signals, including environmental and nutritional events, into a defined and ordered set of cellular responses at the transcriptional level. It has now been shown that all three PPAR isoforms (alpha, beta/delta and gamma) can participate in the regulation of inflammation responses.
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Targeting cancer-promoting inflammation — have anti-inflammatory therapies come of age?

Nature Reviews Clinical Oncology, 2021
Michael Karin
exaly  

Anti-inflammatory action of steroid inhalers.

The Journal of the Association of Physicians of India, 1994
With mucosal inflammation contributing to the pathogenesis of asthma, it is increasingly accepted that long term steroid inhalers may induce remission in chronic long standing asthmatics. The present study involved 44 stable asthmatics who were randomly given either beclomethasone dipropionate inhaler (50 ug) 2 puffs qds or salbutamol inhaler (100 mcg)
V S, Taskar, A A, Mahashur, P J, John, V P, Kolhatkar, L, Menon, S, Bijur   +5 more
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