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Dendrimers as anti-inflammatory agents [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2013 Dendrimers constitute an intriguing class of macromolecules which find applications in a variety of areas including biology. These hyperbranched macromolecules with tailored backbone and surface groups have been extensively investigated as nanocarriers for gene and drug delivery, by molecular encapsulation or covalent conjugation.
Ashok K. Kakkar +3 more
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Nonsteroid Anti-Inflammatory Agents [PDF]
Annual Review of Pharmacology, 1968 The treatment of rheumatic diseases by anti-inflammatory drugs is a re cent development, except for the use of salicylates. The use of cortisone and of phenylbutazone dates from about the same time (93, 233), with the first publications in 1949.
S J Piliero, M Weiner
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Flavonoids as anti-inflammatory agents [PDF]
Proceedings of the Nutrition Society, 2010 Epidemiological evidence suggests that a high intake of plant foods is associated with lower risk of chronic diseases. However, the mechanism of action and the components involved in this effect have not been identified clearly. In recent years, the scientific community has agreed to focus its attention on a class of secondary metabolites extensively ...
SERAFINI, MAURO, Peluso I, Raguzzini A.
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Pyrazoles and Pyrazolines as Anti-Inflammatory Agents [PDF]
Molecules, 2021 The five-membered heterocyclic group of pyrazoles/pyrazolines plays important role in drug discovery. Pyrazoles and pyrazolines present a wide range of biological activities. The synthesis of the pyrazolines and pyrazole derivatives was accomplished via the condensation of the appropriate substituted aldehydes and acetophenones, suitable chalcones and ...
Martha Mantzanidou +2 more
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Anti-Inflammatory Drugs as Anticancer Agents [PDF]
International Journal of Molecular Sciences, 2020 Inflammation is strictly associated with cancer and plays a key role in tumor development and progression. Several epidemiological studies have demonstrated that inflammation can predispose to tumors, therefore targeting inflammation and the molecules involved in the inflammatory process could represent a good strategy for cancer prevention and therapy.
Zappavigna S. +7 more
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Anti-Inflammatory Properties of Anesthetic Agents [PDF]
Critical Care, 2017 AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
Patricia R. M. Rocco +2 more
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Zeitschrift für Naturforschung C, 2007 The pyrrole derivatives 1a, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to ...
Mosaad S. Mohamed +3 more
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Anti-inflammatory Agents: Present and Future [PDF]
Cell, 2010 Inflammation involving the innate and adaptive immune systems is a normal response to infection. However, when allowed to continue unchecked, inflammation may result in autoimmune or autoinflammatory disorders, neurodegenerative disease, or cancer.
Charles A. Dinarello +1 more
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Plants as Sources of Anti-Inflammatory Agents [PDF]
Molecules, 2020 Plants represent the main source of molecules for the development of new drugs, which intensifies the interest of transnational industries in searching for substances obtained from plant sources, especially since the vast majority of species have not yet been studied chemically or biologically, particularly concerning anti-inflammatory action.
Clara dos Reis Nunes +7 more
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Heparin as an Anti-Inflammatory Agent [PDF]
, 2020 ABSTRACTTimely control of the cytokine release syndrome (CRS) at the severe stage of COVID-19 is key to improving the treatment success and reducing the mortality rate. The inhibition of the activity of the two key cytokines, IFNγ and IL-6, can significantly reduce or even reverse the development of the cytokine storm.
Leandar Litov +11 more
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