Results 91 to 100 of about 96,395 (289)
Formulation of topical non-steroidal anti-inflammatory agents [PDF]
, 1987 Reversed-pahse high-performance liquid chromatographic (HPLC) methods were developed for the assay of indomethacin, its decomposition products, ibuprofen and its (tetrahydro-2-furanyl)methyl-, (tetrahydro-2-(2H)pyranyl)methyl- and cyclohexylmethyl esters. The development and application of these HPLC systems were studied.
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Some aspects of the pharmacology of ibufenac, a non-steroidal anti-inflammatory agent
Journal of Pharmacy and Pharmacology, 1968 Abstract When given orally to animals ibufenac has a range of potencies 2 to 4 times that of aspirin. It also suppresses thurfyl nicotinate erythema in man. Like certain other analgesic-anti-inflammatory-antipyretic drugs, when administered intravenously it suppresses bradykinin-induced bronchoconstriction in the guinea-pig.
J. S. Nicholson, P. Hebborn, S. S. Adams
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Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism
Advanced Science, EarlyView.Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang +4 more
wiley +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2017 This study includes design and synthesis of new non-steroidal anti-inflammatory agents (NSAIDs) with expected cyclooxygenase-2 (COX-2) selective inhibition to achieve better activity and low gastric side effects.
Nadeem A. Abdul Razzak +2 more
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Prophylactic non-steroidal anti-inflammatory drugs for the prevention of macular oedema after cataract surgery. [PDF]
, 2016 BACKGROUND: Macular oedema (MO) is the accumulation of extracellular fluid in the central retina (the macula). It may occur after cataract surgery and may give rise to poor visual outcome, with reduced visual acuity and distortion of the central vision ...
Bunce, Catey +5 more
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Advanced Science, EarlyView.Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao +16 more
wiley +1 more source
Management of patients with chronic nonspecific lumbar pain
Медицинский совет, 2019 Chronic lumbar pain (CLP) is one of the most common causes of temporary disability. Both the elimination of specific causes of pain and the assessment of social and psychological factors of pain management are of great importance in the examination of ...
V. A. Parfenov
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A case of new-onset vitiligo in a patient on tofacitinib and brief review of paradoxical presentations with other novel targeted therapies [PDF]
, 2020 With recent advancements in the understanding of vitiligo pathogenesis, Janus kinase (JAK) inhibitors have emerged as a promising new treatment modality, but their effects remain incompletely elucidated.
Alikhan, Mujahed +4 more
core
Topical diclofenac: Clinical effectiveness and current uses in osteoarthritis of the knee and soft tissue injuries [PDF]
, 2008 Background: Diclofenac is a commonly used non-steroidal anti-inflammatory drug (NSAID) for symptom control in osteoarthritis (OA) of the knee and soft tissue injuries.
Banning, M
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Advanced Science, EarlyView.Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu +18 more
wiley +1 more source