Results 71 to 80 of about 21,849 (255)
Chemically modified tetracyclines: The novel host modulating agents
Journal of Indian Society of Periodontology, 2015 Periodontal pathogens and destructive host responses are involved in the initiation and progression of periodontitis. The emergence of host response modulation as a treatment concept has resulted from our improved understanding of the pathogenesis of ...
Devulapalli Narasimha Swamy +3 more
doaj +1 more source
Advanced Science, EarlyView.Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan +11 more
wiley +1 more source
A case of delayed maculopapular eruption to ibuprofen and acute urticaria to acetaminophen
SAGE Open Medical Case Reports, 2021 We present the unique case of a 33-year-old male referred to our clinic in search of analgesic options who was found to have a delayed hypersensitivity reaction to ibuprofen manifesting as a maculopapular rash and acute urticaria to acetaminophen.
Jason Wong +3 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo +11 more
wiley +1 more source
Choosing and using non-steroidal anti-inflammatory drugs in haemophilia [PDF]
, 2016 The management of pain and inflammation in haemophilic arthropathy is challenging due to the lack of anti-inflammatory analgesic agents perfectly suitable for this population.
Makris, M. +3 more
core +1 more source
Musculoskeletal pain: determination of clinical phenotypes and the rational treatment approach
Alʹmanah Kliničeskoj Mediciny, 2019 Personalized treatment is one of the basic principles of modern medicine. When administering a treatment, one should consider individual patient characteristics, comorbidities and, what is most important, the prevailing symptoms, as well as the clinical ...
A. E. Karateev
doaj +1 more source
Non-steroidal analgesic and anti-inflammatory agents. [PDF]
BMJ, 1983 3 Nicholson AN, Stone BM. Sleep and wakefulness handbook for flight medical officers. Neuilly-sur-Seine, France: NATO Advisory Group for Aerospace Research and Development, 1982; AGARDograph No 270. 4 Fiorica V, Higgins EA, Iampietro PF, Lategola MT, Davis AW. Phy? siological responses of men during sleep deprivation. J Appl Physiol 1968;24:167-76.
openaire +2 more sources
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Advanced Science, EarlyView.Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
The nitrosterols - A step forward from the steroid anti-inflammatory drugs? [PDF]
, 2005 Nitric oxide (NO)-releasing non-steroidal anti-inflammatory drugs have been shown to have improved efficacy and lower toxicity than their parent agents, and are currently in clinical trials as anti-inflammatory agents.
Doggrell, Sheila A., Doggrell, Sheila
core +1 more source
Translational Neuroscience, 2023 Headache attributed to craniotomy is an underestimated and under-treated condition. Previous studies confirmed the efficacy of preemptive analgesia with non-steroidal anti-inflammatory agents.
Simon Éva +8 more
doaj +1 more source