Results 101 to 110 of about 96,642 (272)
British Journal of Clinical Pharmacology, EarlyView.Aim This study builds on the environmental risk analysis presented in the 2022 National Report on Medicines Use in Italy by the Italian Medicines Agency and aims to assess the environmental risk posed by medicines in Italy and its regions. Methods The analysis selected 90 medicines based on three criteria: high utilization, low predicted no effect ...
Valentina Giunchi +8 more
wiley +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
Indomethacin: A New Non-steroid Anti-inflammatory Agent [PDF]
BMJ, 1963 P. L. Boardman, Hart Fd
openaire +3 more sources
Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies
Chemistry &Biodiversity, EarlyView.Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang +8 more
wiley +1 more source
Chemistry &Biodiversity, Accepted Article.Ziziphus budhensis is a species described in 2015 in Nepal poorly studied for its phytochemical composition and possible bioactivities. In this study, six extracts were obtained from Z. budhensis leaves using ultrasound assisted extraction with solvents in increasing polarity.
Samjhana Bharati +7 more
wiley +1 more source
South African Propolis: Anti‐Helicobacter pylori Activity, Chemistry, and Toxicity
Chemistry &Biodiversity, EarlyView.ABSTRACT Propolis, a resin‐like substance produced by bees, has previously shown antimicrobial activity against the ulcer‐causing gut pathogen Helicobacter pylori. South African propolis, however, was yet to be investigated. This study aimed to investigate a comprehensive range of South African propolis for its antimicrobial activity against H.
Sarhana Dinat +5 more
wiley +1 more source
Non-steroidal anti-inflammatory drug-induced enteropathy
Intestinal Research, 2017 Non-steroidal anti-inflammatory drugs (NSAIDs) are well known to be associated with serious upper gastrointestinal complications, such as peptic ulcer, bleeding, perforation, and obstruction. Recently, attention has been mainly focused on the small bowel
Sung Jae Shin +4 more
doaj +1 more source
arXivThanks to advances in large language models, a new type of software agent, the artificial intelligence (AI) agent, has entered the marketplace. Companies such as OpenAI, Google, Microsoft, and Salesforce promise their AI Agents will go from generating passive text to executing tasks.
arxiv
Non-steroidal anti-inflammatory agents and the gastrointestinal tract [PDF]
Postgraduate Medical Journal, 1986 C. J. Hawkey, K. W. Somerville
openaire +3 more sources