Results 101 to 110 of about 143,635 (330)

Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent

open access: yesJournal of Pharmacy and Pharmacology, 1973
Abstract Some pharmacological actions of curcumin (diferuloyl methane) have been examined in rats, mice and cats. The compound possesses significant anti-inflammatory activity in acute as well as in chronic models of inflammation. It is as potent as phenylbutazone in the carrageenan oedema test but only half as potent in chronic tests ...
R C Srimal, B N Dhawan
openaire   +3 more sources

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

open access: yesAdvanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou   +15 more
wiley   +1 more source

The use of topical diclofenac in the pain management of osteoarthritis of the knee [PDF]

open access: yes, 2006
Osteoarthritis (OA) is a common complaint that affects millions of people worldwide. As there is no cure for OA, drug treatment is the main form of management.
Banning, M
core  

An Off‐the‐Shelf Artificial Blood Clot Hydrogel Neutralizing Multiple Proinflammatory Mediators for Pro‐Regenerative Periodontitis Treatment

open access: yesAdvanced Science, EarlyView.
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu   +14 more
wiley   +1 more source

Real-practice thromboprophylaxis in atrial fibrillation [PDF]

open access: yes, 2017
This retrospective observational study was based on databases of the Local Health Authority of Treviso, Italy. It evaluated the prevalence and the effectiveness of oral anticoagulation treatment (OAT) for the management of nonvalvular atrial fibrillation
Bettiol, Alessandra   +8 more
core   +2 more sources

Carbon‐Coated Probiotics Restore Intestinal Homeostasis to Promote Damage Repair in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
Carbon‐coated Lactobacillus rhamnosus GG (C dots@LGG) enhances the antioxidant effects of LGG and safeguards the probiotics to target the inflamed colon. This reduces inflammation and oxidative damage, repairs the intestinal barrier, regulates the microbiota, and alleviates colitis.
Xue Chen   +9 more
wiley   +1 more source

Topical agents or dressings for pain in venous leg ulcers. [PDF]

open access: yes, 2010
Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings.
Briggs, M   +2 more
core   +2 more sources

Tendon Aging: A Silent Enemy Revealed Strategies for Effective Treatment

open access: yesAGING MEDICINE, EarlyView.
This review commences with the mechanism of tendon aging, mainly introducing the aging of tendons induced by oxidative stress, hyperglycemia, inflammatory response, cell apoptosis, and fatty infiltration and the association with the tendon stem/progenitor cells, aiming to explore the mechanism of aging and find related treatment methods.
Wenhui Gu   +3 more
wiley   +1 more source

The treatment of asthma with leukotriene receptor antagonists [PDF]

open access: yes, 1999
Over the past three decades the pharmacotherapy of asthma has been based on glucocorticoids, ß2 agonists and theophyllines. Research conducted over the past 10 years has led to greater understanding of the cellular and molecular basis of asthma ...
Cordina, Maria
core  

Orbital inflammatory complications of Crohn’s disease: a rare case series [PDF]

open access: yes, 2018
Orbital inflammatory disease is a rare ophthalmic manifestation of Crohn’s disease. Inflammation is characteristically non-specific, involving one or multiple structures of the orbit.
Abercrombie, Lorraine   +5 more
core   +3 more sources

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