Results 101 to 110 of about 143,635 (330)
Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent
Abstract Some pharmacological actions of curcumin (diferuloyl methane) have been examined in rats, mice and cats. The compound possesses significant anti-inflammatory activity in acute as well as in chronic models of inflammation. It is as potent as phenylbutazone in the carrageenan oedema test but only half as potent in chronic tests ...
R C Srimal, B N Dhawan
openaire +3 more sources
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou+15 more
wiley +1 more source
The use of topical diclofenac in the pain management of osteoarthritis of the knee [PDF]
Osteoarthritis (OA) is a common complaint that affects millions of people worldwide. As there is no cure for OA, drug treatment is the main form of management.
Banning, M
core
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu+14 more
wiley +1 more source
Real-practice thromboprophylaxis in atrial fibrillation [PDF]
This retrospective observational study was based on databases of the Local Health Authority of Treviso, Italy. It evaluated the prevalence and the effectiveness of oral anticoagulation treatment (OAT) for the management of nonvalvular atrial fibrillation
Bettiol, Alessandra+8 more
core +2 more sources
Carbon‐coated Lactobacillus rhamnosus GG (C dots@LGG) enhances the antioxidant effects of LGG and safeguards the probiotics to target the inflamed colon. This reduces inflammation and oxidative damage, repairs the intestinal barrier, regulates the microbiota, and alleviates colitis.
Xue Chen+9 more
wiley +1 more source
Topical agents or dressings for pain in venous leg ulcers. [PDF]
Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings.
Briggs, M+2 more
core +2 more sources
Tendon Aging: A Silent Enemy Revealed Strategies for Effective Treatment
This review commences with the mechanism of tendon aging, mainly introducing the aging of tendons induced by oxidative stress, hyperglycemia, inflammatory response, cell apoptosis, and fatty infiltration and the association with the tendon stem/progenitor cells, aiming to explore the mechanism of aging and find related treatment methods.
Wenhui Gu+3 more
wiley +1 more source
The treatment of asthma with leukotriene receptor antagonists [PDF]
Over the past three decades the pharmacotherapy of asthma has been based on glucocorticoids, ß2 agonists and theophyllines. Research conducted over the past 10 years has led to greater understanding of the cellular and molecular basis of asthma ...
Cordina, Maria
core
Orbital inflammatory complications of Crohn’s disease: a rare case series [PDF]
Orbital inflammatory disease is a rare ophthalmic manifestation of Crohn’s disease. Inflammation is characteristically non-specific, involving one or multiple structures of the orbit.
Abercrombie, Lorraine+5 more
core +3 more sources