Results 111 to 120 of about 993,667 (346)

How Can Network-Pharmacology Contribute to Antiepileptic Drug Development? [PDF]

, 2014
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of exquisitely selective drugs. What is
Di Ianni, Mauricio Emiliano, Talevi, Alan   +1 more
core   +1 more source

Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro‐inflammatory and anti‐inflammatory agents: key role for TNF‐α [PDF]

, 2008
Sylwia Michlewska, Ian Dransfield, Ian L. Megson, Adriano G. Rossi   +3 more
openalex   +1 more source

Application of Anti-Inflammatory Agents in Prostate Cancer [PDF]

, 2020
Koji Hatano, Kazutoshi Fujita, Norio Nonomura   +2 more
openalex   +1 more source

Synthesis and Biological Evaluation of Novel Fusidic Acid Derivatives as Two-in-One Agent with Potent Antibacterial and Anti-Inflammatory Activity [PDF]

, 2022
Borong Tu, Nana Cao, Bingjie Zhang, Wende Zheng, Jiahao Li, Xiaowen Tang, Kaize Su, Jinxuan Li, Zhen Zhang, Zhenping Yan, Dongli Li, Xi Zheng, Kun Zhang, W. David Hong, Panpan Wu   +14 more
openalex   +1 more source

Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation—A Case Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT New‐onset refractory status epilepticus (NORSE) arises without an identifiable cause or prior epilepsy history, with a 16%–27% mortality rate and significant long‐term neurological sequelae. Neuromodulation such as deep brain stimulation (DBS) targeting the anterior and centromedian thalamic nuclei has shown promise when the traditional ...
Mengxuan Tang, Amerta Bai, Felipe Rodridgues Marques Ferreira, Sandipan Pati, Thaddeus Walczak, Benjamin Miller, Oladi Bentho, Thomas Henry, Ilo Leppik, Minoo Shams, Zhiyi Sha, Zachary Sanger, Theoden I. Netoff, Thomas Lisko, Anant Naik, Robert McGovern III, Sima Patel   +16 more
wiley   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Anti-inflammatory Therapy Before Reperfusion Therapy in Patients with Ischemic Vascular Disease on the Incidence of Ischemic Reperfusion Injury: An Evidence-Based Case Report

Acta Medica Indonesiana
Background: Reperfusion serves as a mainstay therapy in almost all ischemic vascular diseases (IVD), but reperfusion may enhance cell damage after an ischemic period time.
Dono Antono, Ade Gautama, Nindya P.B.S Utami   +2 more
doaj   +2 more sources

Effect of Resveratrol on periodontal pathogens during experimental periodontitis in rats

Brazilian Oral Research
The objective of this study was to investigate the antibacterial effect of resveratrol against putative periodontal pathogens during the progression of experimental periodontitis in rats.
Fabiano Ribeiro CIRANO, Renato Correa Viana CASARIN, Fernanda Vieira RIBEIRO, Marcio Zaffalon CASATI, Suzana Peres PIMENTEL, Tiago TAIETE, Maria Martha BERNARDI   +6 more
doaj   +1 more source

Novel hydrogel with Carrageenan, Fucoidan and Titanium oxide nanoparticles for periodontal drug delivery [PDF]

Journal of Oral Health and Oral Epidemiology
Background: Nonsurgical periodontal therapy combined with antimicrobial agents is crucial for effective periodontal care. As local drug delivery systems, hydrogels offer significant advantages for managing periodontal disease. Carrageenan, extracted from
Priyangha Ponmudi Thangavel, Arokia Rajkumar Shancy Merlin, Balaji Ganesh Subramanian   +2 more
doaj   +1 more source