Results 141 to 150 of about 857,317 (238)

Versatile Platinum(IV) Prodrugs of Naproxen and Acemetacin as Chemo-Anti-Inflammatory Agents. [PDF]

Cancers (Basel), 2023
Aputen AD, Elias MG, Gilbert J, Sakoff JA, Gordon CP, Scott KF, Aldrich-Wright JR.   +6 more
europepmc   +1 more source

Glepaglutide‐Loaded Foam for the Induction of Mucosal Healing in the Treatment of Inflammatory Bowel Disease

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang, William Van den Bossche, Hafsa Yagoubi, Espoir K Kambale, Khadija Wahni, Tanya Saxena, Léo Guilbaud, Tom G. Moreels, Joris Messens, Ana Beloqui   +9 more
wiley   +1 more source

Effects of anti-inflammatory agents on clinical outcomes in people with chronic kidney disease: a systematic review and meta-analysis of randomized control trials. [PDF]

Clin Kidney J
Webster ER, Perkovic A, Neuen BL, Tuttle KR, Perkovic V.   +4 more
europepmc   +1 more source

Datura stramonium Flowers as a Potential Natural Resource of Bioactive Molecules: Identification of Anti-Inflammatory Agents and Molecular Docking Analysis. [PDF]

Molecules, 2023
Damergi B, Essid R, Fares N, Khadraoui N, Ageitos L, Ben Alaya A, Gharbi D, Abid I, Rashed Alothman M, Limam F, Rodríguez J, Jiménez C, Tabbene O.   +12 more
europepmc   +1 more source

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan, Hyunjin Kim, Bomin Kim, Honglin Piao, Joon Young Jang, Tae Kyeom Kang, Wook‐Bin Lee, Dohyeon Kim, Seunghyun Jo, Duckhyang Shin, Sharif MD Abuzar, Myung L. Kim, Jaeseok Yang, Sangyong Jon   +13 more
wiley   +1 more source

<i>In vitro</i> and <i>in vivo</i> characterization of oridonin analogs as anti-inflammatory agents that regulate the NF-κB and NLRP3 inflammasome axis. [PDF]

Front Pharmacol
Ou H, Wu Z, Ning J, Huang Q, Wang W, Yang G, Zhou Y, Hou A, Li P, Chen L, Jin WB.   +10 more
europepmc   +1 more source

Curcumin and Its Derivatives as Potential Antimalarial and Anti-Inflammatory Agents: A Review on Structure-Activity Relationship and Mechanism of Action. [PDF]

Pharmaceuticals (Basel), 2023
Jamil SNH, Ali AH, Feroz SR, Lam SD, Agustar HK, Mohd Abd Razak MR, Latip J.   +6 more
europepmc   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

GLP-1 receptor agonists as promising anti-inflammatory agents in heart failure with preserved ejection fraction. [PDF]

Heart Fail Rev
Bonfioli GB, Rodella L, Metra M, Vizzardi E.   +3 more
europepmc   +1 more source

Topical Anti-Inflammatory Agents for Non-Infectious Uveitis: Current Treatment and Perspectives. [PDF]

J Inflamm Res, 2022
Balasubramaniam B, Chong YJ, Azzopardi M, Logeswaran A, Denniston AK.   +4 more
europepmc   +1 more source