Dendrimers as anti-inflammatory agents
Dendrimers constitute an intriguing class of macromolecules which find applications in a variety of areas including biology. These hyperbranched macromolecules with tailored backbone and surface groups have been extensively investigated as nanocarriers ...
Pramod K. Avti, Ashok Kakkar
doaj +1 more source
The glucocorticoid receptor in inflammatory processes : transrepression is not enough [PDF]
Glucocorticoids (GCs) are the most commonly used anti-inflammatory agents to treat inflammatory and immune diseases. However, steroid therapies are accompanied by severe side-effects during long-term treatment. The dogma that transrepression of genes, by
Dejager, Lien +3 more
core +2 more sources
Treatment of ankylosing spondylitis and extra-articular manifestations in everyday rheumatology practice [PDF]
The SpAs are a group of overlapping, chronic, inflammatory rheumatic diseases including AS, a chronic inflammatory disease primarily affecting the SI joints.
Elewaut, Dirk, Matucci-Cerinic, Marco
core +1 more source
The pyrrole derivatives 1a, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to ...
Mosaad S, Mohamed +3 more
openaire +2 more sources
The potential therapeutic use of renin-angiotensin system inhibitors in the treatment of inflammatory diseases [PDF]
Inflammation is a normal part of the immune response to injury or infection but its dysregulation promotes the development of inflammatory diseases, which cause considerable human suffering.
Avan, Amir +5 more
core +1 more source
Modelling Neuroinflammation in vitro: a tool to test the potential neuroprotective effect of anti-inflammatory agents [PDF]
Neuron-microglia co-cultures treated with pro-inflammatory agents are a useful tool to study neuroinflammation in vitro, where to test the potential neuroprotective effect of anti-inflammatory compounds.
Carme Solà +6 more
core +8 more sources
The Anti-Inflammatory Effect of Novel Antidiabetic Agents
The incidence of type 2 diabetes (T2DM) has been increasing worldwide and remains one of the leading causes of atherosclerotic disease. Several antidiabetic agents have been introduced in trying to regulate glucose control levels with different ...
Panagiotis Theofilis +6 more
doaj +1 more source
The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]
1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
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Inflammation: What’s There and What’s New?
Since the dawn of man, inflammation has been known to humanity, as it is marked by pain. Inflammation processes are related to serious chronic diseases with irreversible damage to the organism, being crucial for the development of anti-inflammatory ...
Ricardo C. Calhelha +5 more
doaj +1 more source
A peptide mimic of the chemotaxis inhibitory protein of Staphylococcus aureus: towards the development of novel anti-inflammatory compounds [PDF]
Complement factor C5a is one of the most powerful pro-inflammatory agents involved in recruitment of leukocytes, activation of phagocytes and other inflammatory responses.
AJ Wright +26 more
core +1 more source

