Histamine release inhibition in anti-inflammatory mechanism [PDF]
Rats were depleted of skin histamine by more than 80 % by intraperitoneal injections of sinomenine with daily increasing doses for 6 days. In these rats, egg-white edema induced in the hind paws was inhibited by 68 % of control. The weight of the wall of
Irino, Shozo+3 more
core +1 more source
A Review on Phytochemicals and Biological Properties of Golden Chamomile (Matricaria aurea) [PDF]
Golden chamomile (Matricaria aurea) is widely distributed in Europe and Asia and is commonly used as an alternative to M. chamomilla in traditional medicine in some countries.
Saeed Ghasemi, Fatemeh Yousefbeyk*
doaj +1 more source
Desensitization for the prevention of drug hypersensitivity reactions [PDF]
Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Sung-Yoon Kang+2 more
doaj +1 more source
Synthesis and biological evaluation of new quinoxaline derivatives as antioxidant and anti-inflammatory agents [PDF]
We report the synthesis, anti-inflammatory and antioxidant activities of novel quinoxaline and quinoxaline 1,4-di-N-oxide derivatives. Microwave assisted methods have been used in order to optimize reaction times and to improve the yields.
Aldana, I. (Ignacio)+10 more
core +1 more source
The pyrrole derivatives 1a, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to ...
Mosaad S. Mohamed+3 more
openaire +3 more sources
Anti-inflammatory Agents: Present and Future [PDF]
Inflammation involving the innate and adaptive immune systems is a normal response to infection. However, when allowed to continue unchecked, inflammation may result in autoimmune or autoinflammatory disorders, neurodegenerative disease, or cancer.
Charles A. Dinarello+1 more
openaire +4 more sources
Short-acting β2-agonist prescriptions in patients with asthma: findings from the South Korean cohort of SABINA III [PDF]
Background/Aims Despite short-acting β2-agonist (SABA) overuse being associated with poor asthma outcomes, data on SABA use in South Korea is scarce.
Kwang-Ha Yoo+6 more
doaj +1 more source
Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]
Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria+10 more
core +1 more source
Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity. [PDF]
Although immunotherapies have achieved remarkable salutary effects among subgroups of advanced cancers, most patients do not respond. We comprehensively evaluated biomarkers associated with the "cancer-immunity cycle" in the pan-cancer setting in order ...
Dressman, Devin+13 more
core +1 more source
Anti-leishmanial and Anti-inflammatory Agents from Endophytes: A Review
Leishmaniases and chronic inflammatory diseases are the cause of millions of deaths in the world each year. The treatment of leishmaniasis is facing serious drawbacks particularly due to the limited number of effective medicines, the resistance, and the ...
Rufin Marie Kouipou Toghueo
doaj +1 more source