Results 71 to 80 of about 758,673 (297)

Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: a review

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Inflammation and disease are closely related. Inflammation can induce various diseases, and diseases can promote inflammatory response, and two possibly induces each other in a bidirectional loop.
Ming Bian, Qian-qian Ma, Yun Wu, Huan-huan Du, Gong Guo-hua   +4 more
doaj   +1 more source

Marine Anti-inflammatory and Antioxidant Agents 2.0

, 2023
The Special Issue “Marine Anti-Inflammatory and Antioxidants Agents 2.0” collects in vitro and/or in vivo experimental investigations highlighting the role of marine-derived bioactive compounds as modulators of inflammation and/or oxidative stress ...

core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung

, 2014
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
Tait, M A, Robb, C T, Haslett, C, Duffin, R, Fox, S, Rossi, A G, Dorward, D A, Lucas, C D; id_orcid, Allen, K C, Hirani, N, Marwick, J A   +10 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Evaluation of basil extract ( Ocimum basilicum L.) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents

Brazilian Journal of Pharmaceutical Sciences, 2017
Ocimum is one of the most important genera of the Lamiaceae family. Several studies about basil and its popular use reveal many characteristics of the herb, including its use as antioxidant, anti-aging, anti-inflammatory, anti-carcinogenic, anti ...
Camila Martins Güez, Raul Oliveira de Souza, Paula Fischer, Maria Fernanda de Moura Leão, Jonathaline Apollo Duarte, Aline Augusti Boligon, Margareth Linde Athayde, Luísa Zuravski, Luís Flávio Souza de Oliveira, Michel Mansur Machado   +9 more
doaj   +1 more source

Atividade anti-inflamatória do ácido arjunóli-co extraído de Combretum leprosum Mart. & Eicher (Combretaceae) em camundongos [PDF]

, 2011
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.Combretum leprosum (mofumbo ou cipoaba) é um arbusto nativo do Brasil utilizado na medicina popular para o tratamento de hemorragias, como sedativo ...
Cabrera, Celeste Heisecke
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Relação entre anticorpos anti-Saccharomyces cerevisiae (ASCA) e anti-Helicobacter pylori em pacientes com espondiloartrite axial: um estudo comparativo com doença de Crohn [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2013.Introdução: Espondiloartrites (SpA) são doenças musculoesqueléticasinflamatórias crônicas ...
Rodrigues, Igor Kunze
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