Results 191 to 200 of about 696,361 (266)

Box-Behnken Design Optimization of High-Pressure Processed Bitter Melon (<i>Momordica charantia</i>) Leaf Extract Enhancing Phytochemicals, Anticancer, and Anti-Inflammatory Activities. [PDF]

Int J Mol Sci
Kulchim K, Braspaiboon S, Pitchakarn P, Imsumran A, Buacheen P, Laowanitwattana T, Temviriyanukul P, Chairatvit K, Wongnoppavich A.   +8 more
europepmc   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Pomolic Acid from the Dong Botanical Drug Madeng'ai Suppresses TNF-α-Induced Inflammatory Response in RA-HFLS by Inhibiting NF-κB Signaling Pathway Activation. [PDF]

Molecules
Huang S, Cai W, Wang Y, Xing X, Zhang Z.
europepmc   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

Advanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar, Deeksha Kumaresh, Eduardo Nombera Bueno, Mae Pryor, Paula T. Hammond   +4 more
wiley   +1 more source

Preclinical evaluation of cysteine protease-inhibitor aloxistatin (E64d) for heart failure therapy. [PDF]

J Mol Med (Berl)
Jordan M, Stucki-Koch A, Schinke M, Willmer L, Senne I, Abbas N, Bentele M, Oldenkott D, Lachmann N, Feldbrügge L, Puffert R, Fangmann J, Ramm R, Thum T, Sewald K, Schmidt K, Fiedler J.   +16 more
europepmc   +1 more source

Tissue‐Adhesive Fabric‐Based Bioelectronics for Wearable and Implantable Applications

Advanced Functional Materials, EarlyView.
An implantable and wearable bioelectronic textile (iTextile) is introduced as a unified platform bridging wearable and implantable systems. By integrating a self‐healing polymer, stretchable silk fabric, conductive composite electrodes, and an adhesive hydrogel, the platform enables conformal, stable interfacing with soft tissues. The iTextile supports
Soojung An, Yewon Kim, Kyoungryong Kim, Heewon Choi, Sungjun Yoon, Jaewon Ju, Mikyung Shin, Donghee Son   +7 more
wiley   +1 more source

Neuroprotectin D1 regulating the inflammation and nerve restoration in <i>Aspergillus fumigatus</i> keratitis. [PDF]

Int J Ophthalmol
Li H, Jia YY, Wu MQ, Zhang LN, Lin J, Wang Q, Li C, Zhao GQ.   +7 more
europepmc   +1 more source

Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines

Advanced Functional Materials, EarlyView.
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang, Daniel P. Mayer, Prabhat K. Purbey, Yingzi Liu, Kindra Kelly‐Scumpia, Clara Kang, Natalie Tsubamoto, Dhriti Bolangadi, Iqra Arshad, Charisse Ng, Maksim V. Plikus, Dino Di Carlo, Jason S. Weinstein, Philip O. Scumpia   +13 more
wiley   +1 more source