Novel Tricyclic Flavonoids as Promising Anti-MRSA Agents. [PDF]
Pharmaceuticals (Basel)Background: Methicillin-resistant Staphylococcus aureus (MRSA) is considered the main cause of nosocomial and community-associated infections. Because of antimicrobial resistance, MRSA infections are difficult or impossible to treat, leading to high mortality rates and significant economic and societal costs.
Moldovan CV +6 more
europepmc +4 more sources
Impact of biohybrid magnetite nanoparticles and moroccan propolis on adherence of methicillin resistant strains of staphylococcus aureus [PDF]
, 2016 Biofilm bacteria are more resistant to antibiotics than planktonic cells. Propolis possesses antimicrobial activity. Generally, nanoparticles containing heavy metals possess antimicrobial and antibiofilm properties.
Ana Costa +18 more
core +2 more sources
Frontiers in Microbiology, 2020 Methicillin-resistant Staphylococcus aureus (MRSA) is recognized as one of the serious pathogen that causes acquired infections worldwide. Its emerging need to discover novel, safe and potent anti-MRSA drugs. In this study, primary screening by anti-MRSA
Zhiyu Chen +7 more
doaj +1 more source
Molecular Details of Actinomycin D-Treated MRSA Revealed via High-Dimensional Data
Marine Drugs, 2022 Methicillin-resistant Staphylococcus aureus (MRSA) is highly concerning as a principal infection pathogen. The investigation of higher effective natural anti-MRSA agents from marine Streptomyces parvulus has led to the isolation of actinomycin D, that ...
Xuewei Xia +7 more
doaj +1 more source
Antimicrobial activity of phenolic compounds identified in wild mushrooms, SAR analysis and docking studies [PDF]
, 2013 Aim and Methods: Although the antimicrobial activity of extracts from several mushroom species have been reported, studies with the individual compounds present in that extracts are scarce.
Abreu, Rui M.V. +5 more
core +1 more source
Confounding by indication affects antimicrobial risk factors for methicillin-resistant Staphylococcus aureus but not vancomycin-resistant enterococci acquisition [PDF]
, 2014 Background: Observational studies rarely account for confounding by indication, whereby empiric antibiotics initiated for signs and symptoms of infection prior to the diagnosis of infection are then viewed as risk factors for infection.
Hilary Placzek +7 more
core +3 more sources
Journal of Arrhythmia, 2018 An 86‐year‐old woman suffering from repeated methicillin‐resistant Staphylococcus aureus (MRSA) bacteremia underwent percutaneous lead extraction using an excimer laser. Since negative blood cultures were confirmed three times after lead extraction under
Masatsugu Nozoe +6 more
doaj +1 more source
The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. [PDF]
, 2020 HT61 is a small quinolone-derived compound previously demonstrated to exhibit bactericidal activity against gram-positive bacteria including methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). When
Amison, RT +6 more
core +1 more source
Fucoidan-loaded, neutrophil membrane-coated nanoparticles facilitate MRSA-accompanied wound healing
Materials & Design, 2023 Treatment of methicillin-resistant Staphylococcus aureus (MRSA)-infected wounds remains an important clinical challenge. Current treatments using vancomycin usually result in high side effects with low treatment efficacy because of strong drug toxicity ...
Jingyi Li +6 more
doaj +1 more source
Decreases in Antimicrobial Use Associated With Multihospital Implementation of Electronic Antimicrobial Stewardship Tools. [PDF]
, 2020 BackgroundAntimicrobial stewards may benefit from comparative data to inform interventions that promote optimal inpatient antimicrobial use.MethodsAntimicrobial stewards from 8 geographically dispersed Veterans Affairs (VA) inpatient facilities ...
Butler, Jorie M +10 more
core +1 more source