Results 261 to 270 of about 2,533,954 (307)

Anti‐neutrophil cytoplasm antibodies (ANCA)

Australian and New Zealand Journal of Medicine, 1990
AbstractCirculating antibodies directed against cytoplasmic constituents of granulocytes and monocytes (anti‐neutrophil cytoplasm antibodies, ANCA) are found in about 80% of active cases of Wegener's granulomatosis and microscopic polyarteritis. Antibodies are detected by indirect immunofluorescence on normal peripheral blood leucocytes, or by ELISA or
J A, Savige, D J, Davies
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Anti-neutrophil cytoplasmic antibodies in uveitis

Current Eye Research, 1990
The antineutrophil cytoplasmic antibody test has become available over the past 4 or 5 years. It is positive in a limited number of conditions whose characteristic feature is the presence of a small vessel vasculitis. These include Wegener's granulomatosis and microscopic polyarteritis. The test was applied to 63 patients with uveitis of various types.
D W, Young, S, Dring, R, Thompson
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Anti-Neutrophil Cytoplasmic Antibodies Positivity and Anti-Leukotrienes in Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Monocentric Study on 134 Italian Patients

International Archives of Allergy and Immunology, 2019
Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitis associated with asthma, anti-neutrophil cytoplasmic antibodies (ANCA) positivity, and tissue eosinophilia.
J. Schroeder, M. Folci, L. Losappio, M. Chevallard, R. Sinico, C. Mirone, Fabrizio de Luca, M. Nichelatti, E. Pastorello   +8 more
semanticscholar   +1 more source

Pitfalls with anti-neutrophil cytoplasmic antibodies (ANCA)

Clinical Rheumatology, 1989
A 39-year-old Ugandan student is described presenting with general malaise, fever and a pulmonary infiltrate. Open lung biopsy showing infarction and positive ANCA lead to a diagnosis of Wegener's granulomatosis and a treatment with immunosuppressive drugs was instituted.
L S, De Clerck, J F, Van Offel, W A, Smolders, F A, Empsten, C H, Bridts, N, Bourgeois, E, Van Marck, U, Timmermans, W J, Stevens   +8 more
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Anti-neutrophil cytoplasm antibody associated vasculitis

The International Journal of Biochemistry & Cell Biology, 2003
Anti-neutrophil cytoplasm antibody associated vasculitides are autoimmune diseases that require treatment with powerful immunosuppressants in order to avert life threatening complications, principally renal failure and lung haemorrhage. Their pathogenesis remains unclear but the circulating autoantibodies are almost certainly instrumental in mediating ...
Peter, Hewins, Caroline, Savage
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Myelodysplasia, Vasculitis and Anti-Neutrophil Cytoplasm Antibodies

Leukemia & Lymphoma, 1993
A cutaneous or systemic vasculitis occurs in myelodysplasia as well as in myeloproliferative and lymphoproliferative disorders. The most common lesion is a leucocytoclastic vasculitis, with neurological or joint involvement occurring less often. The vasculitis may appear contemporaneously with or precede the clinical onset of the blood dyscrasia ...
J A, Savige, L, Chang, C L, Smith, J C, Duggan   +3 more
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Disease Associations with Anti-Neutrophil Cytoplasmic Antibodies

1993
The discovery of autoantibodies to components of neutrophil cytoplasm, widely known as anti-neutrophil cytoplasmic antibodies (ANCA), has led to great advances in the diagnosis and monitoring of patients with primary systemic vasculitis. The antigenic targets of ANCA have been identified as neutrophil granule constituents, and it appears that the ...
C D, Pusey, G, Gaskin
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Antineutrophil cytoplasmic antibodies

The Lancet, 2006
Much like other autoantibodies (eg, anti-double stranded DNA in systemic lupus erythematosus or antiglomerular basement membrane antibodies in Goodpasture's syndrome), antineutrophil cytoplasmic antibodies (ANCA) have provided doctors with a useful serological test to assist in diagnosis of small-vessel vasculitides, including Wegener's granulomatosis,
Bosch, Xavier, Guilabert, Antonio, Font, Josep   +2 more
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Anti-Neutrophil Cytoplasmic Antibodies (ANCA) and Infection

1993
As ANCA are occasionally noted in patients with infectious disorders independently of any vasculitis process, we examined serum from patients with acute infection (n = 22) and septic shock (n = 57). Only two patients with acute infection were ANCA positive as determined by indirect immunofluorescence and western blot analysis.
J L, Mege, J C, Escallier, C, Capo, P, Bongrand, J G, Velut, N, Quiles, J, Soubeyrand, J M, Durand   +7 more
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Anti-Neutrophil Cytoplasm Antibodies in HIV Infection

1993
Sera from 105 HIV-infected patients were tested for anti-neutrophil cytoplasm antibodies (ANCA) by indirect immunofluorescence (IIF), by specific ELISAs using target proteins of ANCA and by a neutrophil cytoplasm extract ELISA. Forty-four sera were positive. These included 18 positive by IIF, 7 with anti-neutrophil proteinase 3 antibodies, 26 with anti-
J A, Savige, L, Chang, S M, Crowe
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