Results 161 to 170 of about 72,801 (208)

Anti-neutrophil cytoplasm antibody associated vasculitis

The International Journal of Biochemistry & Cell Biology, 2003
Anti-neutrophil cytoplasm antibody associated vasculitides are autoimmune diseases that require treatment with powerful immunosuppressants in order to avert life threatening complications, principally renal failure and lung haemorrhage. Their pathogenesis remains unclear but the circulating autoantibodies are almost certainly instrumental in mediating ...
Peter, Hewins, Caroline, Savage
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Anti-neutrophil cytoplasmic antibodies in uveitis

Current Eye Research, 1990
The antineutrophil cytoplasmic antibody test has become available over the past 4 or 5 years. It is positive in a limited number of conditions whose characteristic feature is the presence of a small vessel vasculitis. These include Wegener's granulomatosis and microscopic polyarteritis. The test was applied to 63 patients with uveitis of various types.
D W, Young, S, Dring, R, Thompson
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Antineutrophil cytoplasmic antibodies

The Lancet, 2006
Much like other autoantibodies (eg, anti-double stranded DNA in systemic lupus erythematosus or antiglomerular basement membrane antibodies in Goodpasture's syndrome), antineutrophil cytoplasmic antibodies (ANCA) have provided doctors with a useful serological test to assist in diagnosis of small-vessel vasculitides, including Wegener's granulomatosis,
X, Bosch, J, Font, E, Mirapeix
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Myelodysplasia, Vasculitis and Anti-Neutrophil Cytoplasm Antibodies

Leukemia & Lymphoma, 1993
A cutaneous or systemic vasculitis occurs in myelodysplasia as well as in myeloproliferative and lymphoproliferative disorders. The most common lesion is a leucocytoclastic vasculitis, with neurological or joint involvement occurring less often. The vasculitis may appear contemporaneously with or precede the clinical onset of the blood dyscrasia ...
J A, Savige, L, Chang, C L, Smith, J C, Duggan   +3 more
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Pitfalls with anti-neutrophil cytoplasmic antibodies (ANCA)

Clinical Rheumatology, 1989
A 39-year-old Ugandan student is described presenting with general malaise, fever and a pulmonary infiltrate. Open lung biopsy showing infarction and positive ANCA lead to a diagnosis of Wegener's granulomatosis and a treatment with immunosuppressive drugs was instituted.
L S, De Clerck, J F, Van Offel, W A, Smolders, F A, Empsten, C H, Bridts, N, Bourgeois, E, Van Marck, U, Timmermans, W J, Stevens   +8 more
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Anti-neutrophil cytoplasmic antibodies and anti-endothelial cell antibodies

Pediatric Nephrology, 1991
Anti-neutrophil cytosolic antibodies (ANCA) and anti-endothelial cell antibodies (AECA) have been identified in a wide variety of disorders, but their pathophysiological role remains unclear. ANCA appear to be particularly associated with various forms of vasculitis including Wegener's granulomatosis.
M J, Dillon, E J, Tizard
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Clinical significance of positive anti‐neutrophil cytoplasmic antibodies without evidence of anti‐neutrophil cytoplasmic antibodies‐associated vasculitis

International Journal of Rheumatic Diseases, 2019
AbstractAimAnti‐neutrophil cytoplasmic antibodies (ANCA) have a role in the diagnostic workup of ANCA‐associated vasculitis. However, the clinical significance of positive ANCA in the absence of vasculitis is yet to be determined. Therefore, we sought to investigate the clinical spectrum and rate of patients with a positive ANCA without evidence of ...
Gil Bornstein, Ilan Ben‐Zvi, Nadav Furie, Chagai Grossman   +3 more
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Anti-Neutrophil Cytoplasmic Antibodies (ANCA) and Infection

1993
As ANCA are occasionally noted in patients with infectious disorders independently of any vasculitis process, we examined serum from patients with acute infection (n = 22) and septic shock (n = 57). Only two patients with acute infection were ANCA positive as determined by indirect immunofluorescence and western blot analysis.
J L, Mege, J C, Escallier, C, Capo, P, Bongrand, J G, Velut, N, Quiles, J, Soubeyrand, J M, Durand   +7 more
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Anti-Neutrophil Cytoplasm Antibodies in HIV Infection

1993
Sera from 105 HIV-infected patients were tested for anti-neutrophil cytoplasm antibodies (ANCA) by indirect immunofluorescence (IIF), by specific ELISAs using target proteins of ANCA and by a neutrophil cytoplasm extract ELISA. Forty-four sera were positive. These included 18 positive by IIF, 7 with anti-neutrophil proteinase 3 antibodies, 26 with anti-
J A, Savige, L, Chang, S M, Crowe
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Disease Associations with Anti-Neutrophil Cytoplasmic Antibodies

1993
The discovery of autoantibodies to components of neutrophil cytoplasm, widely known as anti-neutrophil cytoplasmic antibodies (ANCA), has led to great advances in the diagnosis and monitoring of patients with primary systemic vasculitis. The antigenic targets of ANCA have been identified as neutrophil granule constituents, and it appears that the ...
C D, Pusey, G, Gaskin
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