Results 221 to 230 of about 37,560 (244)

Pitfalls with anti-neutrophil cytoplasmic antibodies (ANCA)

Clinical Rheumatology, 1989
A 39-year-old Ugandan student is described presenting with general malaise, fever and a pulmonary infiltrate. Open lung biopsy showing infarction and positive ANCA lead to a diagnosis of Wegener's granulomatosis and a treatment with immunosuppressive drugs was instituted.
L S, De Clerck, J F, Van Offel, W A, Smolders, F A, Empsten, C H, Bridts, N, Bourgeois, E, Van Marck, U, Timmermans, W J, Stevens   +8 more
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Anti-neutrophil cytoplasmic antibodies and anti-endothelial cell antibodies

Pediatric Nephrology, 1991
Anti-neutrophil cytosolic antibodies (ANCA) and anti-endothelial cell antibodies (AECA) have been identified in a wide variety of disorders, but their pathophysiological role remains unclear. ANCA appear to be particularly associated with various forms of vasculitis including Wegener's granulomatosis.
M J, Dillon, E J, Tizard
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Clinical significance of positive anti‐neutrophil cytoplasmic antibodies without evidence of anti‐neutrophil cytoplasmic antibodies‐associated vasculitis

International Journal of Rheumatic Diseases, 2019
AbstractAimAnti‐neutrophil cytoplasmic antibodies (ANCA) have a role in the diagnostic workup of ANCA‐associated vasculitis. However, the clinical significance of positive ANCA in the absence of vasculitis is yet to be determined. Therefore, we sought to investigate the clinical spectrum and rate of patients with a positive ANCA without evidence of ...
Gil Bornstein, Ilan Ben‐Zvi, Nadav Furie, Chagai Grossman   +3 more
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Anti-Neutrophil Cytoplasmic Antibodies (ANCA) and Infection

1993
As ANCA are occasionally noted in patients with infectious disorders independently of any vasculitis process, we examined serum from patients with acute infection (n = 22) and septic shock (n = 57). Only two patients with acute infection were ANCA positive as determined by indirect immunofluorescence and western blot analysis.
J L, Mege, J C, Escallier, C, Capo, P, Bongrand, J G, Velut, N, Quiles, J, Soubeyrand, J M, Durand   +7 more
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Anti-Neutrophil Cytoplasm Antibodies in HIV Infection

1993
Sera from 105 HIV-infected patients were tested for anti-neutrophil cytoplasm antibodies (ANCA) by indirect immunofluorescence (IIF), by specific ELISAs using target proteins of ANCA and by a neutrophil cytoplasm extract ELISA. Forty-four sera were positive. These included 18 positive by IIF, 7 with anti-neutrophil proteinase 3 antibodies, 26 with anti-
J A, Savige, L, Chang, S M, Crowe
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Disease Associations with Anti-Neutrophil Cytoplasmic Antibodies

1993
The discovery of autoantibodies to components of neutrophil cytoplasm, widely known as anti-neutrophil cytoplasmic antibodies (ANCA), has led to great advances in the diagnosis and monitoring of patients with primary systemic vasculitis. The antigenic targets of ANCA have been identified as neutrophil granule constituents, and it appears that the ...
C D, Pusey, G, Gaskin
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IgA nephropathy with anti-neutrophil cytoplasmic antibody seropositivity

Clinical Nephrology, 2015
There are few reports of IgA nephropathy (IgAN) with antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis.The authors report the clinical and pathological findings in 14 patients with IgAN and ANCA seropositivity.These retrospective cases consisted of 4 men and 10 women with a mean age of 44.4 ± 12.7 years.
Xin, Huang, Yuan, Wang, Lijiao, Xie, Ying, Zhang, Sha, Tang, Shiwei, Yin, Xuejing, Gao, Juan, Cai, Weili, Wang, Jun, Zhang, Jinghong, Zhao, Yunjian, Huang, Yafei, Li, Jingbo, Zhang   +13 more
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Anti-neutrophil cytoplasmic antibody-associated glomerulonephritis in children

Pediatric Nephrology, 1993
Two cases of anti-neutrophil cytoplasmic antibody (ANCA)-associated necrotizing and crescentic glomerulonephritis are reported. A 12-year-old girl and a 10-year-old boy presented with polyarthritis, anaemia, haematuria, proteinuria, impaired renal function, anorexia, nausea, marked loss of weight and lethargy.
M C, Nash, C L, Jones, R G, Walker, H R, Powell   +3 more
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Anti-Neutrophil Cytoplasmic Antibodies in Generalized Autoimmune Diseases

International Archives of Allergy and Immunology, 1996
Anti-neutrophil cytoplasmic antibodies (ANCA) are a system of autoantibodies which are strongly associated with the primary systemic vasculitides (PSV). cANCA, as detected by indirect immunofluorescence, are mostly reactive to proteinase 3 (PR3) and bear high sensitivity and specificity for Wegener's granulomatosis.
A, Schnabel, S, Hauschild, W L, Gross
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Renal transplantation in anti-neutrophil cytoplasmic antibody vasculitis

Expert Review of Clinical Immunology, 2018
Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) has the propensity to acquire a devastating disease course. Despite the advances in therapeutics, a significant proportion of patients progress to end-stage renal disease (ESRD). Renal transplantation is being increasingly employed in this population, with gradual improvement in outcomes ...
D, Geetha, S, Kant
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