Enhancement of platelet response to immune complexes and IgG aggregates by lipid A-rich bacterial lipopolysaccharides. [PDF]
, 1978 The effect of the common lipid moiety of bacterial LPS on secretion from washed human platelets has been studied. The lipid A-rich LPS of S. minnesota R595 and a lipid A preparation both potentiated platelet serotonin secretion in response to IgG ...
Ginsberg, MH, Henson, PM
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Hydralazine-associated antineutrophil cytoplasmic antibody vasculitis with pulmonary-renal syndrome [PDF]
, 2018 Hydralazine, a vasodilator, is commonly used as an adjunctive treatment for moderate to severe hypertension, heart failure and hypertensive emergencies in pregnancy. Hydralazine-induced lupus was first described in 1953. Clinical presentation ranges from
Aeddula, Narothama Reddy +3 more
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Use of Plasmapheresis and Immunosuppressants to Treat Diffuse Alveolar Hemorrhage in a Patient with Granulomatosis with Polyangiitis. [PDF]
, 2019 Granulomatosis with polyangiitis (GPA) is a systemic granulomatous inflammatory disease characterized by small-to-medium vessel vasculitis due to Central Anti-Neutrophil Cytoplasmic Antibody (C-ANCA).
Sattar, Yasar +4 more
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ANCA-positive vasculitis: Clinical implications of ANCA types and titers [PDF]
, 2016 INTRODUCTION: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune disease that can affect multiple organs, the kidney being one of the most affected.
Domingues, V., Machado, B., Santos, J.
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A case of myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated glomerulonephritis and concurrent membranous nephropathy [PDF]
, 2013 BACKGROUND: Myeloperoxidase anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (MPO-ANCA-GN) and concurrent membranous nephropathy (MN) are very rare combination. Their causal relationship has been suggested, but not determined.
Hideaki Yamabe +8 more
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BMC OphthalmologyBackground Necrotizing scleritis is one of the most destructive ocular manifestations of underlying systemic diseases that can lead to a variety of severe complications, including globe perforation or vision loss.
Mohammadreza Tahavvori +4 more
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Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex [PDF]
, 2011 VACV gene C16L encodes a 37-kDa protein that is highly conserved in orthopoxviruses and functions as an immunomodulator. Intranasal infection of mice with a virus lacking C16L (vΔC16) induced less weight loss, fewer signs of illness and increased ...
Peters, Nicholas Edward +1 more
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BMC Infectious DiseasesBackground Existing studies indicate that infection may serve as both initiators and accelerators in the pathogenesis of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) through multiple immunopathological pathways.
Xinyu Li +5 more
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Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome [PDF]
, 2011 Background Pulmonary-renal syndrome associated with anti-glomerular basement membrane (GBM) antibodies, also known as Goodpasture's syndrome, is a rare but acute and life-threatening condition.
Christoph Etter +6 more
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Relapse in Anti-Neutrophil Cytoplasm Antibody (ANCA)–Associated Vasculitis [PDF]
Kidney International Reports, 2020 Clinical relapses are common in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis, necessitating repeated treatment with immunosuppressive therapy, and increasing the risks of severe adverse events. Better understanding the basis of relapse would help stratify patients, testing the notion that more treatment may prevent development of ...
openaire +4 more sources