Results 81 to 90 of about 72,801 (208)

Relationship between tumour PTEN/Akt/COX-2 expression, inflammatory response and survival in patients with colorectal cancer [PDF]

, 2016
In patients with colorectal cancer (CRC), local and systemic inflammatory responses have been extensively reported to associate with cancer survival. However, the specific signalling pathways responsible for inflammatory responses are not clear. The PTEN/
Bennett, Lindsay, Edwards, Joanne, Horgan, Paul G., McMillan, Donald C., Park, James, Powell, Arfon G.M.T., Roseweir, Antonia K., Van Wyk, Hester C.   +7 more
core   +3 more sources

C13orf31 (FAMIN) is a central regulator of immunometabolic function. [PDF]

, 2016
Single-nucleotide variations in C13orf31 (LACC1) that encode p.C284R and p.I254V in a protein of unknown function (called 'FAMIN' here) are associated with increased risk for systemic juvenile idiopathic arthritis, leprosy and Crohn's disease.

core   +2 more sources

Screening of a HUVEC cDNA library with transplant-associated coronary artery disease sera identifies RPL7 as a candidate autoantigen associated with this disease. [PDF]

, 2001
A HUVEC cDNA library was screened with sera from two patients who had developed transplant-associated coronary artery disease (TxCAD) following cardiac transplantation.
Linke, A.T., Marchant, B., Marsh, P., Frampton, Geoffrey, Murphy, John J., Rose, Marlene L.   +5 more
core   +4 more sources

Autoantibody profiles and their association with blood eosinophils in asthma and COPD

Allergology International, 2017
Background: Autoimmune involvement in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD) has been proposed, and autoantibodies are a hallmark of autoimmunity.
Koji Tamai, Harukazu Yoshimatsu, Toshiharu Saito, Hirofumi Matsuoka, Nobuhiko Okada, Yasuko Koma, Akiko Otsuka, Nao Oda, Sayaka Inoue, Sachie Kume, Yujiro Suzuki   +10 more
doaj   +1 more source

ANCA-associated vasculitis – Should we change the standard of care? [PDF]

, 2015
Collaborative clinical trials over the last 25 years have revolutionised the care of patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. This has led to production of management recommendations and standards of care.
Bligny, Bourgarit, Choi, de Groot, De Groot, Fauci, Faurschou, Finkielman, Flossmann, Ghosh, Guillevin, Han, Harper, Hauer, Hoffman, Jayne, Jennette, Jennette, Koldingsnes, Leavitt, Luqmani, Mahr, Masi, Mooney, Mooney, Mukhtyar, Mukhtyar, Mukhtyar, Mukhtyar, Nataraja, Ntatsaki, Pagnoux, Pradhan, Rahmattulla, Rao, Reinhold-Keller, Sharma, Sorensen, Stone, Stone, Suppiah, Talar-Williams, Walsh, Watts, Watts, Watts   +45 more
core   +1 more source

Carbimazole-induced agranulocytosis – A rare case report

Journal of Dr. NTR University of Health Sciences, 2018
A 30-year-old lady with hyperthyroidism for the past 1 year was initially on carbimazole 30 mg twice orally and then changed to 30 mg once daily.
R Siddeswari, Sikandar Mohan, K Swamy
doaj   +1 more source

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo [PDF]

, 2013
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2. Once outside the
Afonso, P., Angermann, B., Germain, R., Kastenmüller, W., Lämmermann, T., Parent, C., Wang, J.   +6 more
core   +2 more sources

Anti-neutrophil cytoplasmic antibodies and their clinical significance

Clinical Rheumatology, 2018
Anti-neutrophil cytoplasmic antibodies (ANCA) are a group of autoantibodies that cause systemic vascular inflammation by binding to target antigens of neutrophils. These autoantibodies can be found in serum from patients with systemic small-vessel vasculitis and they are considered as a biomarker for ANCA-associated vasculitis (AAV).
Suwanchote, Supaporn, Rachayon, Muanpetch, Rodsaward, Pongsawat, Wongpiyabovorn, Jongkonnee, Deekajorndech, Tawatchai, Wright, Helen L, Edwards, Steven W, Beresford, Michael W, Rerknimitr, Pawinee, Chiewchengchol, Direkrit   +9 more
openaire   +3 more sources

Anti-neutrophil cytoplasmic antibodies and vasculitis [PDF]

Postgraduate Medical Journal, 1990
B, Leaker, G, Cambridge
openaire   +2 more sources

Combination therapy with rituximab and cyclophosphamide in the treatment of anti-neutrophil cytoplasmic antibodies (ANCA) positive pulmonary hemorrhage: case report

Pediatric Rheumatology Online Journal, 2011
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with pulmonary hemorrhage is rare in childhood. Standard treatment includes corticosteroids and cyclophosphamide (CYC), which is associated with a high level of toxicity. We report a
Lehman Thomas JA, Baird Emily M, Worgall Stefan   +2 more
doaj   +1 more source