Results 1 to 10 of about 1,149,142 (304)

Autoimmunity to a ribonucleoprotein drives neuron loss in multiple sclerosis models

Neurobiology of Disease, 2022
Neurodegeneration, the progressive loss or damage to neurons and axons, underlies permanent disability in multiple sclerosis (MS); yet its mechanisms are incompletely understood.
Cole D. Libner, Hannah E. Salapa, Catherine Hutchinson, Todd E. Stang, Patricia A. Thibault, S. Austin Hammond, Michael C. Levin   +6 more
doaj   +1 more source

Anti-dense fine speckled (DFS) antibody: its staining pattern in indirect immunofluorescence and its clinical relevance

Romanian Journal of Internal Medicine, 2022
Background: Dense fine speckled (DFS) pattern is defined by very intense, heterogeneous speckled staining of nucleoplasms of interphase HEp-2 cells and chromosomal areas of metaphase cells. The association of Anti-DFS70 and rheumatologic signs, symptoms,
Karahan Samet, Emre Şerife, Hörmet-Öz Hatice T.   +2 more
doaj   +1 more source

Seroprevalence of AIH-related autoantibodies in patients with acute hepatitis E viral infection: a prospective case–control study in China

Emerging Microbes and Infections, 2020
The seroprevalenc of autoimmune hepatitis (AIH)-related antibodies in patients, particularly Asians, with acute hepatitis E (AHE) is unclear. In this study, we investigated whether acute hepatitis E virus (HEV) infection is associated with the ...
Jian Wu, Naizhou Guo, Lifei Zhu, Xueyan Zhang, Cunquan Xiong, Jun Liu, Yanping Xu, Jun Fan, Jiong Yu, Qiaoling Pan, Jinfeng Yang, Hanying Liang, Xiuyuan Jin, Sunyi Ye, Wei Wang, Chengyuan Liu, Jinrong Zhang, Gongqi Li, Bin Jiang, Hongcui Cao, Lanjuan Li   +20 more
doaj   +1 more source

The clinical and immunological profiles of systemic lupus erythematosus patients from Assam, North-East India

Indian Journal of Rheumatology, 2020
Objective: The objective of this study is to document the clinical and immunological profiles of systemic lupus erythematosus (SLE) patients from the Upper Assam region and to evaluate the relevance of autoantibody combinations on the clinical ...
Debashree Talukdar, Akash Protim Gogoi, Daisy Doley, Rebecca R Marak, Sanjeeb Kakati, Vandana Pradhan, Anita H Nadkarni, Shashi Baruah   +7 more
doaj   +1 more source

Prevalence and Significance of Autoantibody Seropositivity in Children with Wilson’s Disease

Diagnostics, 2023
Autoantibodies occur in healthy subjects as well as in children with Wilson’s disease (WD), but their prevalence and significance are unknown. Thus, we aimed to assess the prevalence of autoantibodies and autoimmune markers, and their relationship to ...
Wojciech Jańczyk, Joanna B. Bierła, Ilona Trojanowska, Aldona Wierzbicka-Rucińska, Bożena Cukrowska, Piotr Socha   +5 more
doaj   +1 more source

Anti-nuclear antibody expression in severe scrub typhus infection: Preliminary observations

Journal of Global Infectious Diseases, 2014
John Victor Peter, Mathew F Griffith, John Antony Jude Prakash, Anugragh Chrispal, Kishore Pichamuthu, George M Varghese   +5 more
doaj   +2 more sources

Development of Candidate Antigens for Rapid Test Kit to Detect Autoantibodies in Patients with Systemic Lupus Erythematosus

Research Journal of Life Science, 2017
Systemic Lupus Erythematosus (LES) is an autoimmune inflammatory disease characterized by the formation of anti-nuclear antibodies (ANA) and anti-double stranded DNA (anti-dsDNA) antibodies as diagnostic markers. Detection of such autoantibodies requires
Wisnu Barlianto, Hani Susianti, Singgih Wahono, Nelly Ismayasih, Rossy Meilani, Kusworini Handono   +5 more
doaj   +1 more source

Anti-Tn Monoclonal Antibody Attenuates Hyperoxia-Induced Lung Injury by Inhibiting Oxidative Stress and Inflammation in Neonatal Mice

Frontiers in Pharmacology, 2020
Maternal immunization with Tn vaccine increases serum anti-Tn antibody titers and attenuates hyperoxia-induced lung injury in neonatal rats. This study determined whether anti-Tn monoclonal antibody can protect against hyperoxia-induced lung injury in ...
Chung-Ming Chen, Chung-Ming Chen, Jaulang Hwang, Hsiu-Chu Chou, Chinde Chen   +4 more
doaj   +1 more source

Anti-nuclear antibodies in patients with breast cancer [PDF]

Clinical and Experimental Immunology, 2018
Summary To study the prevalence of anti-nuclear antibodies (ANA) in breast cancer patients and its association with tumour characteristics. Ninety-one patients with breast mass detected by image studies and assigned to conduct diagnostic biopsy and eventual surgical treatment were studied for demographical, tumour data and presence of ...
R Nisihara, M C C Machoski, A Neppel, C A Maestri, I Messias-Reason, T L Skare   +5 more
openaire   +2 more sources

Case report of a lupus patient with flare and symptomatic cardiac tamponade and macrophage activation syndrome: A biochemical diagnostic perspective

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2022
Systemic lupus erythematosus (SLE) is an autoimmune disorder with multifactorial etiology involving vital organs like the heart and causing rare complications like cardiac tamponade which are indeed difficult to manage especially in a setting of ...
Amandeep Singh, Kapil Bhatia, Pratibha Misra, Bhasker Mukherjee, Vivek N Ambade   +4 more
doaj   +1 more source