Results 131 to 140 of about 314,014 (260)

Expression and Functional Evaluation of Recombinant Anti-receptor Activator of Nuclear Factor Kappa-B Ligand Monoclonal Antibody Produced in Nicotiana benthamiana [PDF]

, 2021
Wanuttha Boonyayothin, Sirorut Sinnung, Balamurugan Shanmugaraj, Yoshito Abe, Richard Strasser, Prasit Pavasant, Waranyoo Phoolcharoen   +6 more
openalex   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Molecular Signatures of Anti-nuclear Antibodies: Contributions of Specific Light Chain Residues and a Novel New Zealand BlackVκ1Germline Gene [PDF]

, 2003
Zhiyan Liang, Cui Chen, Chandra Mohan
openalex   +1 more source

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

Autoimmune diseases in vitiligo: do anti-nuclear antibodies decrease thyroid volume? [PDF]

, 2003
Georg Zettinig, Adrian Tanew, Gustavo Brandão Fischer, Wolfgang R. Mayr, Robert Dudczak, M Weissel   +5 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Autoantibodies from primary biliary cirrhosis patients with anti-p95c antibodies bind to recombinant p97/VCP and inhibitin vitronuclear envelope assembly [PDF]

, 2004
Kiyomitsu Miyachi, Yasuhiro Hirano, Tuneyoshi Horigome, Tsuneyo Mimori, Hiroshi Miyakawa, Yasushi Onozuka, M Shibata, M. Hirakata, Akira Suwa, Hiroo Hosaka, S. Matsushima, Tatsuji Komatsu, Hiroshi Matsushima, Raleigh Hankins, Marvin J. Fritzler   +14 more
openalex   +1 more source

Internal iamin structures within G1 nuclei of human dermal fibroblasts [PDF]

, 1993
The nuclear lamina is a mesh-like network of fibres subjacent to the inner nuclear membrane that is believed to be involved in the specific spatial reorganisation of chromatin after mitosis.
Bridger, JM, Hutchison, CJ, Kill, IR, O’Farrell, M   +3 more
core  

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Treponemal Antibodies in Non-Syphilitic, Positive Anti-Nuclear Factor Sera**From the Department of Clinical Laboratories and Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.

, 1966
Thomas R. Neblett, Lucile R. Merriam, Gerald Fine, Thomas K. Burnham   +3 more
openalex   +1 more source