The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease [PDF]
, 2018 Yuriy Baglaenko +13 more
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Heterogeneity of anti-nuclear antibodies in autoimmune liver diseases
Biomedicine & Pharmacotherapy, 1999 M. Nishioka, S.A. Morshed
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Anti-nuclear factor as an auto-antibody
, 1962 The study of a factor which can be demonstrated using Coons indirect fluorescent antibody technique, in the serum of patients with Systemic Lupus Erythematosus (and some other diseases) has been described. An outline of the historical development of the concept of auto-immune disease has been presented, incorporating the technical advances which ...
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Advanced Functional Materials, EarlyView.The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
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Does serum anti-nuclear antibody predict outcomes of pregnancy among women with a history of recurrent pregnancy loss, without coexisting anti-phospholipid antibody syndrome ? A systematic review and meta-analysis [PDF]
, 2019 Trenton L. Place +6 more
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Relevance of systematic anti-nuclear antibodies testing after obstetrical complications
, 2021 Marie Koubi +9 more
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Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo
Advanced Functional Materials, EarlyView.This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić +9 more
wiley +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
Advanced Functional Materials, EarlyView.This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer +10 more
wiley +1 more source