Presence of anti-nuclear antibody associated with worse clinical outcomes of anti-NMDAR encephalitis [PDF]
PurposeSystemic autoantibodies are important for the diagnosis of autoimmune diseases, but their roles in anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis are unknown.
Chunyan Lei +5 more
doaj +2 more sources
Anti-nuclear antibody screening using HEp-2 cells. [PDF]
The American College of Rheumatology position statement on ANA testing stipulates the use of IIF as the gold standard method for ANA screening(1). Although IIF is an excellent screening test in expert hands, the technical difficulties of processing and reading IIF slides--such as the labor intensive slide processing, manual reading, the need for ...
Buchner C, Bryant C, Eslami A, Lakos G.
europepmc +4 more sources
Automated Processing and Evaluation of Anti-Nuclear Antibody Indirect Immunofluorescence Testing [PDF]
Indirect immunofluorescence (IIF) is considered by the American College of Rheumatology (ACR) and the international consensus on ANA patterns (ICAP) the gold standard for the screening of anti-nuclear antibodies (ANA).
Vincent Ricchiuti +4 more
doaj +2 more sources
Evaluation of Anti-Nuclear antibody test results in clinical practice [PDF]
Objective: Aim of this study is to evaluate anti-nuclear antibody (ANA) test results obtained between 2009 and 2011.Methods: Of a totally 5068 cases tested for ANA by indirect immunofluorescence method (IIFA), randomly chosen 982 ANA-positive cases were ...
Nevreste Celikbilek +2 more
doaj +5 more sources
Anti-Nuclear Antibody (ANA) Positivity and Nuclear Antigen Reactivity in Patients with Joint Hypermobility Syndrome/Hypermobile Ehlers Danlos Syndrome (JHS/hEDS) [PDF]
Background/Objectives: To compare clinical features of patients with joint hypermobility syndrome/hypermobile Ehlers Danlos Syndrome (JHS/hEDS) who tested positive or negative for anti-nuclear antibodies (ANA), and to determine antibody titers, staining ...
Lindsay Moy +2 more
doaj +2 more sources
Determination of Anti-nuclear Antibody Pattern Distribution and Clinical Relationship. [PDF]
Autoantibodies are immunglobulins occurred directly against autoantigens that are known as endogen antigens. Autoimmune disease is an occasion that the body begins a fight against its own cells and tissues. The antibodies that are created by the body against its own cell nuclei are called as anti-nuclear antibodies (ANA), and one of the methods used ...
Mengeloglu Z +4 more
europepmc +4 more sources
Systemic lupus erythematosus (SLE) is an autoimmune disease associated with several autoantibodies targeted to nuclear and cytoplasmic antigens. Positivity of the serum antinuclear antibody (ANA), double stranded (ds) DNA, anti-smith (sm) antibody are ...
Ajay Kumar Jha, Ashok Sunder
doaj +1 more source
Anti-HMGB1 antibody is a potential characteristic autoantibody for Sjögren's syndrome
Sjögren's syndrome (SS) is a common chronic inflammatory autoimmune disease that affects about 0.33–0.77% population in China. The positive for antinuclear antibodies (ANA) is one of the key features of SS, which shows a nuclear fine speckled (AC-4 ...
Mingkun Chen +7 more
doaj +1 more source
Immunogenicity and Lupus-Like Autoantibody Production Can Be Linked to Each Other along With Type I Interferon Production in Patients with Rheumatoid Arthritis Treated With Infliximab: A Retrospective Study of a Single Center Cohort. [PDF]
Besides anti-drug antibodies, anti-nuclear antibodies and anti-DNA antibodies are often induced in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors.
Yuki Ishikawa +8 more
doaj +1 more source
Diagnostic value of aquaporin 1 and 5 antibodies in primary Sjögren's syndrome
Objective To explore the diagnostic value and clinical relevance of antibodies against aquaporin-1 (anti-AQP1) and aquaporin-5 (anti-AQP5) in primary Sjögren's syndrome (pSS), and investigate new potential biomarkers that can contribute to the diagnosis.
WANG Xiaoyu +3 more
doaj +1 more source

