Results 21 to 30 of about 314,014 (260)

Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]

, 2003
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
BM Friedman, C Boshoff, C Boshoff, D Serraino, D Whitby, DH Kedes, Dimitra Bourboulia, EP Zorrilla, F Sitas, F Vitale, Freddy Sitas, G de-The, G de-The, G Rezza, GR Simpson, H Renwick, J Iscovich, J Ziegler, Janet M Wojcicki, JJ Goedert, JL Ziegler, JL Ziegler, KA Staskus, L Rainbow, Lara Stein, LD Baker, M Dedicoat, Margaret I Urban, Martin Hale, Moosa Patel, P Cook-Mozaffari, P Kellam, Paul Ruff, PS Moore, R Greenblatt, R Newton, R Newton, R Tedeschi, Ranjan Sur, RJ Biggar, Rob Newton, RP Stowe, S Lemeshow, S Plancoulaine, SJ Gao, STATA, Statistics South Africa, TH Bothwell, TH Bothwell, VR Gordeuk, Y Chang, Z Grossman   +51 more
core   +2 more sources

Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]

, 2013
BackgroundVertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Enke, Raymond A, Fuller, John A, Kalesnykas, Giedrius, Merbs, Shannath L, Wahlin, Karl J, Zack, Donald J   +5 more
core   +8 more sources

A Case of Dermatomyositis Coexisting with Both Anti-Mi-2 and Anti-NXP-2 Antibodies

Case Reports in Dermatology, 2020
Myositis-specific autoantibodies (MSAs) including anti-Mi-2 and anti-nuclear matrix protein 2 (NXP-2) antibodies have been detected in the patients with dermatomyositis (DM), and are useful tools for identifying clinical subsets of DM.
Mitsuru Ito, Chie Moriya, Kanako Matsuyama, En Shu, Yasuhito Hamaguchi, Mariko Seishima   +5 more
doaj   +1 more source

Systemic Lupus Erythematosus with Acute Pancreatitis as an Initial Presentation [PDF]

Journal of Clinical and Diagnostic Research, 2018
Systemic Lupus Erythematosus (SLE) is an autoimmune, chronic inflammatory disorder affecting mainly the women. Almost half of the SLE patients have gastrointestinal involvement.
Indira Bairy, Anupam Berwal, Mukhyaprana Prabhu, Lokvendra Singh Budania   +3 more
doaj   +1 more source

Expression and intracellular localization of FKHRL1 in mammary gland neoplasms. [PDF]

, 2004
FKHRL1 (FOXO3a), a member of the Forkhead family of genes, has been considered to be involved in the development of breast tumors; however, the in vivo expression and activation status of FKHRL1 in breast tumors still remains unclear.
Akagi, Tadaatsu, Hayashi, Kazuhiko, Jin, Gui-Shan, Kondo, Eisaku, Liu, Yi-Xuan, Miyake, Takayoshi, Shibata, Masao, Takashima, Takako, Yoshino, Tadashi   +8 more
core   +1 more source

Epitope-Specific Anti-SerpinB3 Antibodies for SerpinB3 Recognition and Biological Activity Inhibition

Biomolecules, 2023
SerpinB3 is a serine protease inhibitor that plays a relevant role in disease progression and cancer by increasing fibrosis, cell proliferation, and invasion, besides conferring resistance to apoptosis.
Alessandra Biasiolo, Michele Sandre, Stefania Ferro, Santina Quarta, Mariagrazia Ruvoletto, Gianmarco Villano, Cristian Turato, Maria Guido, Oriano Marin, Patrizia Pontisso   +9 more
doaj   +1 more source

Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer [PDF]

, 2009
Breast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells.
Arata Shimo, Jae-Hyun Park, Jung-Won Kim, Meng-Lay Lin, Miki Akiyama, Tatsuhiko Tsunoda, Tomomi Ueki, Toshihiko Nishidate, Toyomasa Katagiri, Yataro Daigo, Yusuke Nakamura   +10 more
core   +2 more sources

Involvement of premacular mast cells in the pathogenesis of macular diseases.

PLoS ONE, 2019
We previously reported on the elevated intravitreal activities of tryptase and chymase in association with idiopathic epiretinal membrane (ERM) and idiopathic macular hole (MH).
Takaki Sato, Seita Morishita, Taeko Horie, Masanori Fukumoto, Teruyo Kida, Hidehiro Oku, Kimitoshi Nakamura, Shinji Takai, Denan Jin, Tsunehiko Ikeda   +9 more
doaj   +1 more source

Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus [PDF]

, 2011
Merkel cell polyomavirus (MCV) has been recently described as the cause for most human Merkel cell carcinomas. MCV is similar to simian virus 40 (SV40) and encodes a nuclear large T (LT) oncoprotein that is usually mutated to eliminate viral replication ...
Ali, Binda, Campbell, Campbell, Caplan, Cotsiki, Côté-Martin, DeCaprio, Dilworth, Felici, Feng, Flinn, Hakki, Houben, Jennifer Hein, Lane, Laude, Li, Liang, Linzer, Mannová, Nakamura, Nakamura, Ole V. Gjoerup, Pallas, Patrick S. Moore, Pelkmans, Per H. Basse, Peralta, Pipas, Poupon, Price, Qian, Richardson, Schowalter, Shuda, Shuda, Simon C.W. Richardson, Srinivasan, Sukarieh, Tuna Toptan, Whitman, Wrana, Wurmser, Xi Liu, Yuan Chang   +45 more
core   +2 more sources

Simultaneous paraneoplastic cerebellar degeneration, Lambert-Eaton syndrome and neuropathy associated with AGNA/anti-SOX1 and VGCC antibodies

Neurological Research and Practice, 2021
Anti-glial nuclear antibody (AGNA) is an onconeuroal antibody targeting the nuclei of Bergmann glia in the cerebellum and Anti-SRY-related HMG-box 1 (SOX1).
Jonas Feldheim, Cornelius Deuschl, Martin Glas, Christoph Kleinschnitz, Tim Hagenacker   +4 more
doaj   +1 more source