Results 31 to 40 of about 314,014 (260)

The subnuclear localization of tRNA ligase in yeast [PDF]

, 1987
Yeast tRNA ligase is an enzyme required for tRNA splicing. A study by indirect immune fluorescence shows that this enzyme is localized in the cell nucleus. At higher resolution, studies using indirect immune electron microscopy show this nuclear location
Abelson, John, Clark, Michael W.
core   +1 more source

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei [PDF]

, 1992
Tissue-specific patterns of methylated deoxycytidine residues in the mammalian genome are preserved by postreplicative methylation of newly synthesized DNA. DNA methyltransferase (MTase) is here shown to associate with replication foci during S phase but
Alsner, Altschul, Ascoli, Beck, Bensch, Bestor, Bestor, Bestor, Bestor, Bestor, Brancolini, Bravo, Carmo-Fonseca, Carter, Cook, Czank, D'Andrea, Fox, Fu, Gauthier-Rouvière, Goldman, Gruenbaum, Hatton, Huang, Kaiser, Kambach, Kumar, Lasko, Lauster, Lawrence, Li, Li, Matthias, Meier, Mills, Morris, Nakamura, Nakayasu, Noguchi, O'Keefe, Ottiger, Peculis, Posfai, Roise, Sambrook, Saunders, Spector, Tomkinson, Tubo, Vissel, Wang, Weier   +51 more
core   +1 more source

Detection of circulating B cells producing anti-GPIb autoantibodies in patients with immune thrombocytopenia. [PDF]

PLoS ONE, 2014
BACKGROUND: We previously reported that an enzyme-linked immunospot (ELISPOT) assay for detecting anti-GPIIb/IIIa antibody-secreting B cells is a sensitive method for identifying patients with immune thrombocytopenia (ITP).
Masataka Kuwana, Yuka Okazaki, Yasuo Ikeda   +2 more
doaj   +1 more source

Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting p65. [PDF]

, 2016
Human bocavirus (HBoV), a parvovirus, is a single-stranded DNA etiologic agent causing lower respiratory tract infections in young children worldwide.
A Christensen, A Zhou, AY Chen, B Huang, ET Martin, F Mercurio, H Lukkarinen, HL Luo, J Hiscott, J Napetschnig, J Shen, KA Park, L Unterholzner, L Verstrepen, LF Chen, M Coiras, M Meriluoto, M Severa, MG Santoro, MS Hayden, N Edner, ND Perkins, Q Huang, R Dijkman, RE Randall, RN Silk, RW Korner, S Ghosh, SF Cotmore, T Allander, T Allander, T Lu, T Ursic, TD Gilmore, TE Morrison, W Shen, X Li, XF Deng, Y Hirose, Z Zheng, ZF Zhang   +40 more
core   +1 more source

Serological Evidence for the Association Between Epstein-Barr Virus Infection and Sjögren’s Syndrome

Frontiers in Immunology, 2020
BackgroundExposure to Epstein-Barr virus (EBV) infection has been hypothesized to be an important risk factor for multiple rheumatic diseases, but the serological evidence so far for its role in Sjögren’s syndrome (SjS) is not clearly established yet ...
Jingxiu Xuan, Jingxiu Xuan, Zhiqian Ji, Bin Wang, Xiaoli Zeng, Rongjuan Chen, Rongjuan Chen, Yan He, Yan He, Peishi Rao, Peishi Rao, Puqi Wu, Puqi Wu, Guixiu Shi, Guixiu Shi   +14 more
doaj   +1 more source

The F-actin filament capping protein CapG is a bona fide nucleolar protein [PDF]

, 2008
Actin works in concert with myosin I to regulate the transcription of ribosomal genes in the nucleolus. Recently, nucleolar actin has been shown to be active in its polymeric form raising the question how actin dynamics is regulated in the nucleolus ...
Gettemans, Jan, Hubert, Thomas, Van Impe, Katrien, Vandekerckhove, Joël   +3 more
core   +2 more sources

Retrospective analysis of the clinical significance of Ro52/TRIM21 antibody and specific antinuclear antibody patterns by indirect immunofluorescence

Journal of the Pakistan Medical Association
Objectives: To determine the clinical significance of Ro52 protein/tripartite motif-containing 21 antibody and specific antinuclear antibody patterns using indirect immunofluorescence technique.
Kaifang Liu, Yunfeng Liao, Pu Li, Jing Shi   +3 more
doaj   +1 more source

Arkadia (RING Finger Protein 111) Mediates Sumoylation-Dependent Stabilization of Nrf2 Through K48-Linked Ubiquitination

Cellular Physiology and Biochemistry, 2018
Background/Aims: The transcription factor Nrf2 is a master regulator of the antioxidant defense system, protecting cells from oxidative damage. We previously reported that the SUMO-targeted E3 ubiquitin ligase (STUbL), RING finger protein 4 (RNF4 ...
Deneshia J. McIntosh, Treniqka S. Walters, Ifeanyi J. Arinze, Jamaine Davis   +3 more
doaj   +1 more source

Identifying gene locus associations with promyelocytic leukemia nuclear bodies using immuno-TRAP. [PDF]

, 2013
Important insights into nuclear function would arise if gene loci physically interacting with particular subnuclear domains could be readily identified.
Ahmed, Kashif, Bazett-Jones, David P, Boutros, Paul C, Ching, Reagan W, Penn, Linda Z   +4 more
core   +2 more sources

Autoimmune hepatitis induced by nitrofurantoin. The importance of the autoantibodies for an early diagnosis of immune disease

Clinics and Practice, 2012
Nitrofurantoin has been in use since 1953 as an effective agent for the prevention of recurrent urinary tract infection. It is associated with a wide range of adverse drug reactions.
Jagannath M. Sherigar, Richard Fazio, Minsheng Zuang, Edward Arsura   +3 more
doaj   +1 more source