Results 31 to 40 of about 920,518 (281)

Epitope-Specific Anti-SerpinB3 Antibodies for SerpinB3 Recognition and Biological Activity Inhibition

Biomolecules, 2023
SerpinB3 is a serine protease inhibitor that plays a relevant role in disease progression and cancer by increasing fibrosis, cell proliferation, and invasion, besides conferring resistance to apoptosis.
Alessandra Biasiolo, Michele Sandre, Stefania Ferro, Santina Quarta, Mariagrazia Ruvoletto, Gianmarco Villano, Cristian Turato, Maria Guido, Oriano Marin, Patrizia Pontisso   +9 more
doaj   +1 more source

Involvement of premacular mast cells in the pathogenesis of macular diseases.

PLoS ONE, 2019
We previously reported on the elevated intravitreal activities of tryptase and chymase in association with idiopathic epiretinal membrane (ERM) and idiopathic macular hole (MH).
Takaki Sato, Seita Morishita, Taeko Horie, Masanori Fukumoto, Teruyo Kida, Hidehiro Oku, Kimitoshi Nakamura, Shinji Takai, Denan Jin, Tsunehiko Ikeda   +9 more
doaj   +1 more source

A Case of Dermatomyositis Coexisting with Both Anti-Mi-2 and Anti-NXP-2 Antibodies

Case Reports in Dermatology, 2020
Myositis-specific autoantibodies (MSAs) including anti-Mi-2 and anti-nuclear matrix protein 2 (NXP-2) antibodies have been detected in the patients with dermatomyositis (DM), and are useful tools for identifying clinical subsets of DM.
Mitsuru Ito, Chie Moriya, Kanako Matsuyama, En Shu, Yasuhito Hamaguchi, Mariko Seishima   +5 more
doaj   +1 more source

Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1 [PDF]

, 2014
The Epstein-Barr virus (EBV) nuclear antigen 3 family of protein is critical for the EBV-induced primary B-cell growth transformation process. Using a yeast two-hybrid screen we identified 22 novel cellular partners of the EBNA3s. Most importantly, among
Bazot, Q, Deschamps, T, Gruffat, H, Harth-Hertle, ML, Kempkes, B, Leblanc, P, Lotteau, V, Manet, E, Rabourdin-Combe, C, Siouda, M, Tafforeau, L, Tommasino, M   +11 more
core   +6 more sources

Detection of circulating B cells producing anti-GPIb autoantibodies in patients with immune thrombocytopenia. [PDF]

PLoS ONE, 2014
BACKGROUND: We previously reported that an enzyme-linked immunospot (ELISPOT) assay for detecting anti-GPIIb/IIIa antibody-secreting B cells is a sensitive method for identifying patients with immune thrombocytopenia (ITP).
Masataka Kuwana, Yuka Okazaki, Yasuo Ikeda   +2 more
doaj   +1 more source

Anti-nuclear antibodies in patients with premature ovarian failure [PDF]

Human Reproduction, 1999
We examined the prevalence of anti-nuclear antibodies (ANA) in 32 consecutive patients with premature ovarian failure with and without chromosomal abnormalities. Blood samples were taken for karyotype determination as well as detection of autoantibodies, X-terminal microdeletions and spontaneous follicular growth. The correlation between ANA positivity
B, Ishizuka, Y, Kudo, A, Amemiya, H, Yamada, T, Matsuda, T, Ogata   +5 more
openaire   +2 more sources

Serological Evidence for the Association Between Epstein-Barr Virus Infection and Sjögren’s Syndrome

Frontiers in Immunology, 2020
BackgroundExposure to Epstein-Barr virus (EBV) infection has been hypothesized to be an important risk factor for multiple rheumatic diseases, but the serological evidence so far for its role in Sjögren’s syndrome (SjS) is not clearly established yet ...
Jingxiu Xuan, Jingxiu Xuan, Zhiqian Ji, Bin Wang, Xiaoli Zeng, Rongjuan Chen, Rongjuan Chen, Yan He, Yan He, Peishi Rao, Peishi Rao, Puqi Wu, Puqi Wu, Guixiu Shi, Guixiu Shi   +14 more
doaj   +1 more source

Simultaneous paraneoplastic cerebellar degeneration, Lambert-Eaton syndrome and neuropathy associated with AGNA/anti-SOX1 and VGCC antibodies

Neurological Research and Practice, 2021
Anti-glial nuclear antibody (AGNA) is an onconeuroal antibody targeting the nuclei of Bergmann glia in the cerebellum and Anti-SRY-related HMG-box 1 (SOX1).
Jonas Feldheim, Cornelius Deuschl, Martin Glas, Christoph Kleinschnitz, Tim Hagenacker   +4 more
doaj   +1 more source

RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus [PDF]

, 2011
Epstein-Barr virus (EBV) immortalizes resting B-cells and is a key etiologic agent in the development of numerous cancers. The essential EBV-encoded protein EBNA 2 activates the viral C promoter (Cp) producing a message of ~120 kb that is differentially ...
A Bakos, A Bell, A Dey, A Lin, AI Bell, B Kempkes, B Sugden, BM Peterlin, C Lee, CD Gregory, CF Bourgeois, CH Wu, CH Wu, D Ivanov, DA Gilchrist, DC Hargreaves, DS Gilmour, DS Gilmour, DY Wu, DY Wu, E Johannsen, E Klein, EA Abbate, G Kelly, G Laux, H Gross, H Kirby, Helen M. Webb, I Tempera, J You, JH Yik, JI Cohen, K Fujinaga, KD Robertson, KD Robertson, L Waltzer, L Wang, M Ottinger, M Woisetschlaeger, M Woisetschlaeger, Michelle J. West, MJ West, MK Jang, N Alazard, N Kaplan, NA Brown, NF Marshall, NP Gomes, P Filippakopoulos, Paul M. Lieberman, R Tierney, Richard D. Palermo, S Egloff, S Egloff, S Swaminathan, SH Chao, SJ Bark-Jones, SR Grossman, SY Wu, T Fujita, T Fujita, T Henkel, T Wada, T Wada, U Zimber-Strobl, VT Nguyen, W Lucchesi, W Yue, W Yue, W Yue, W Zhu, X Tong, X Tong, X Tong, YK Kim, Z Yang   +75 more
core   +3 more sources

γδ T cells affect IL-4 production and B-cell tolerance [PDF]

, 2014
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun, Cohen, Finkelman, Gerber, Greg A. Kirchenbaum, Hidaka, Hirose, Hua Huang, Izui, John C. Cambier, Koichi Ikuta, Kubo, Lawrence J. Wysocki, M. Kemal Aydintug, Rebecca L. O’Brien, Ryan A. Heiser, Simon R. Carding, Sperling, Sunaga, Tamara L. Casper, Thiago O. Detanico, Willi K. Born, Yafei Huang   +22 more
core   +1 more source