Results 61 to 70 of about 914,783 (319)
Clinics and Practice, 2012 Nitrofurantoin has been in use since 1953 as an effective agent for the prevention of recurrent urinary tract infection. It is associated with a wide range of adverse drug reactions.
Jagannath M. Sherigar +3 more
doaj +1 more source
Drug-induced anti-Ro positive subacute cutaneous lupus in a man treated with olmesartan [PDF]
, 2019 A 66-year-old man presented to the outpatient dermatology clinic with a chief complaint of a pruritic rash on his upper trunk and proximal upper extremities, which had been present for three weeks.
Farsi, Maheera +4 more
core
Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1 [PDF]
, 2014 The Epstein-Barr virus (EBV) nuclear antigen 3 family of protein is critical for the EBV-induced primary B-cell growth transformation process. Using a yeast two-hybrid screen we identified 22 novel cellular partners of the EBNA3s. Most importantly, among
Bazot, Q +11 more
core +6 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Clinical characteristics of systemic sclerosis complicated with digital ulcers
Pifu-xingbing zhenliaoxue zazhiObjective To explore the characteristics of systemic sclerosis with acro-ulceration (SSc-DUs) and its association with organ involvement and autoantibodies in order to improve the understanding of the disease.
Dongdong CHEN +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Paraneoplastic Brainstem Encephalitis Associated with Anti-Hu Antibody [PDF]
Journal of Neurocritical Care, 2015 Background: Background: Paraneoplastic brainstem encephalitis (PBE) is a rare syndrome and has been described in patients with lung and breast cancer. Several anti-neuronal nuclear antibodies are associated with PBE. Case Report: We experienced a case of
Jee Eun Yoon +4 more
doaj +1 more source
Small and large intestine express a truncated Dab1 isoform that assembles in cell-cell junctions and co-localizes with proteins involved in endocytosis [PDF]
, 2018 Disabled-1 (Dab1) is an essential intracellular adaptor protein in the reelin pathway. Our previous studies in mice intestine showed that Dab1 transmits the reelin signal to cytosolic signalling pathways.
Balda, María S. +5 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence [PDF]
, 2016 AKTIP is a shelterin-interacting protein required for replication of telomeric DNA. Here, we show that AKTIP biochemically interacts with A- and B-type lamins and affects lamin A, but not lamin C or B, expression.
Astrologo, Letizia +14 more
core +2 more sources