Results 271 to 280 of about 219,576 (296)

Targeted Nano-Based Systems for the Anti-Obesity Agent’s Delivery

Obesity is a global health concern and a chronic disease that is accompanied by excessive fat storage in adipose and nonadipose tissues. An increase in the body-mass index (BMI) is directly proportional to the 2- to 3.9-fold increase in all-cause mortality in obesity.
Ayse Basak, Engin, Evren Doruk, Engin, Atilla, Engin   +2 more
openaire   +2 more sources

Bioactive peptides from food proteins as potential anti-obesity agents: Mechanisms of action and future perspectives

Trends in Food Science and Technology, 2023
Indyaswan Tegar Suryaningtyas, Jae-Young Je   +1 more
exaly  

DGAT1 inhibitors as anti-obesity and anti-diabetic agents.

Current opinion in drug discovery & development, 2010
Since 2008, significant advances have been made in understanding the role of diacylglycerol acyl transferase-1 (DGAT1) in disease states such as diabetes and obesity. Gene deletion and overexpression studies have provided important new insights into the function of DGAT1, as have the first reports from preclinical models of small-molecule inhibitor ...
Alan M, Birch, Linda K, Buckett, Andrew V, Turnbull   +2 more
openaire   +1 more source

Alpha-lipoic acid, an anti-obesity agent?

Expert opinion on investigational drugs, 2004
Obesity shortens life expectancy and is a risk factor for hypertension and Type 2 diabetes. When added to the standard chow of Sprague-Dawley or Otsuka Long-Evans Tokushima Fatty rats, alpha-lipoic acid (0.5% weight/weight) reduced body weight and food intake. Alpha-lipoic acid also increased whole-body energy expenditure.
openaire   +4 more sources

Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism

European Journal of Medicinal Chemistry, 2023
Yu-Tao Hu, Shuo-Bin Chen
exaly  

[Sugar as an anti-obesity agent?].

Ugeskrift for laeger, 2000
A V, Astrup, A, Raben
openaire   +1 more source

Clinical trial success rates of anti‐obesity agents: the importance of combination therapies

Obesity Reviews, 2015
A M Sharma
exaly  

Sibutramine: a review of the pharmacology of a novel anti-obesity agent.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1997
Sibutramine is a noradrenaline and 5-hydroxytryptamine reuptake inhibitor which causes weight loss in laboratory rodents via effects on both food intake and metabolic rate. Sibutramine's effects are predominantly mediated by two pharmacologically-active metabolites (its primary and secondary amines).
openaire   +1 more source

Natural anti-obesity agents and their therapeutic role in management of obesity: A future trend perspective

Biomedicine and Pharmacotherapy, 2019
Sravani Karri, Sanjay Sharma, Ketan Hatware   +2 more
exaly  

Engineering yeast to produce plant-derived anti-obesity agent

Nature Chemistry, 2023
openaire   +2 more sources