Results 41 to 50 of about 219,576 (296)

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Adiponectin as novel biomarker of endothelial dysfunction in insulin resistance and obesity – a narrative review

Journal of Education, Health and Sport, 2020
Introduction: Obesity is a chronic fatal disease with still growing incidence among children, adolescents, and adults worldwide. The subclinical inflammatory process together with hipoadiponectinemia may lead to the development of various comorbidities ...
Joanna Szydełko, Paulina Trojanowska, Izabela Dąbrowska, Magdalena Szydełko-Gorzkowicz, Michał Litwińczuk   +4 more
doaj   +1 more source

Lipidated peptides as anti-obesity agents

, 2018
Lipidated peptides, analogs of both forms of the prolactin-releasing peptide, PrRP31 and PrRP20, represent anorexigenic compounds that lower food intake and function in the brain after peripheral administration. The analogs PrRP31 and PrRP20 lipidated at the N-terminus by myristic or palmitic acids bind with high affinity to the endogenous receptor ...
Maletínská, L. (Lenka), Železná, B. (Blanka), Blechová, M. (Miroslava), Popelová, A. (Andrea)   +3 more
openaire   +2 more sources

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Service evaluation of the GOALS family-based childhood obesity treatment intervention during the first 3 years of implementation. [PDF]

, 2014
Objectives: To evaluate the impact of the GOALS (Getting Our Active Lifestyles Started) family-based childhood obesity treatment intervention during the first 3 years of implementation.
Doust, Jenny, Carter, Stacy, Staniford, LJ, Knowles, Zoe, Luis Ayuso-Mateos, Jose, Cassidy, Linda, McCaffery, Kirsten, Murphy, Rebecca C., Bonner, Brendan, Olaya, Beatriz, Rychetnik, Lucie, Bonner, C, Philip A. Gomersall (16670175), Watson, PM, Owen, S., McKinn, Shannon, Heuch, Ingrid, Manchaiah, Vinaya, Griffin, Eve, Galas, Aleksander, Murphy, RC, Irwig, L, Tayebeh Ahmadi (10928763), Dugdill, Lindsey, Rajalakshmi Krishna (3329811), Jansen, J, Watson, Diane E., Teixeira-Pinto, A, Watson, P.M., Hagen, Knut, Kek, Heng Chua, April Camilla Roslani, Hwa, Chia Chai, Allie, Kurt, Carter, SM, Hayen, A, Turner, R, Perry, Ivan J., Gomersall, Philip A.,, Simpson, Judy M., Ayuso Mateos, José Luis, Ida Hilmi, Staniford, Leanne J., Irwig, Les, Randall, Deborah (R14877), Knowles, Z., Corcoran, Paul, Maria Haro, Josep, Nyland, Morten, Vinaya Manchaiah (749633), Heuch, Ivar, Cable, N. Timothy, Haro, Josep Maria, Glasziou, Paul, Hayen, Andrew, Knowles, ZR, Hargreaves, J., David Tomé (9229998), Pickering, K, Staniford, L.J., Cable, N.T., Tome, David, Dugdill, L, Hargreaves, Jackie, Dugdill, L., Kalan, Robyn, Ahmadi, Tayebeh,, Næss, Halvor, O'Carroll, Amanda, Ahmadi, Tayebeh, Jorm, Louisa R. (R11579), Gomersall, Philip A., McCaffery, K, O\u27Carroll, Amanda, Ramafuthole, Tshepiso, Jansen, Jesse, Chatterji, Somnath, Khean, Lee Goh, Cable, NT, Leonardi, Matilde, Ebrahim, Fatima, Glasziou, P, Owen, Stephanie, Lay, Hoong Lian, Lee, Ping Chin, Lujic, Sanja (R12222), Krishna, Rajalakshmi, Tze, Pheng Lau, Doust, J, Garin, Noe, Ayuso-Mateos, Jose Luis, Parker, Lisa, Gałaś, Aleksander, Birkeland, Jon Steinar, Hargreaves, J, Rychetnik, L, Owen, S, Teixeira-Pinto, Armando, Murphy, R.C., Wiysonge, Charles S., Haro Abad, Josep Maria, Krishna, Rajalakshmi,, Knowles, Z, Pickering, Katie, Leonardi, Matilde A., McKinn, S, Sainio, Päivi, Moneta, Maria Victoria, Zwart, John-Anker, Bonner, Carissa, Koyanagi, Ai, Gomersall, Philip, Watson, Paula M., Turner, Robin, Nyland, Harald Inge, Manchaiah, Vinaya,, Tome, David,, Perry, Ivan J, Universitat Autònoma de Barcelona, Engel, Mark Emmanuel, Victoria Moneta, Maria   +120 more
core   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Tackling obesity: new therapeutic agents for assisted weight loss

, 2010
JG Karam1, SI McFarlane21SUNY-Downstate-Kings County Hospital, Brooklyn, NY, USA, Maimonides Medical Center, Brooklyn, NY, USA; 2Division of Endocrinology, College of Medicine, State University of New York-Downstate Medical Center, New York, USAAbstract:
SI McFarlane, JG Karam
core   +1 more source

Novel anti-obesity drugs and plasma lipids

, 2014
Obesity is a health problem of global, epidemic proportions and a major risk factor for chronic diseases resulting in accelerated morbidity and mortality. Dyslipidemia with a predominance of small dense LDL, impaired functionality of HDL particles, and
Toth, PP, Ferlita, A, MONTALTO, Giuseppe, Di Bartolo, V, RIZZO, Manfredi, NIKOLIC, Dragana, Banach, M   +6 more
core   +2 more sources

Interferon tau alleviates obesity-induced adipose tissue inflammation and insulin resistance by regulating macrophage polarization.

PLoS ONE, 2014
Chronic adipose tissue inflammation is a hallmark of obesity-induced insulin resistance and anti-inflammatory agents can benefit patients with obesity-associated syndromes.
Wei Ying, Srikanth Kanameni, Cheng-An Chang, Vijayalekshmi Nair, Stephen Safe, Fuller W Bazer, Beiyan Zhou   +6 more
doaj   +1 more source