Results 61 to 70 of about 126,339 (259)

Characterization of Tunicamycin as Anti-obesity Agent

Biomolecules and Therapeutics, 2009
Abstract － Adipocytes undergo adipocyte stress in the excessive presence of lipid. Adipocyte stress accompanies the typical signs of endoplasmic reticulum (ER) stress: unfolded protein response and overexpression of molecular chaperones. Apoptotic induction in adipocytes is known as a good strategy for treating obesity.
Ha-Suk Song, Hye-Min Kim, Sook-Yung Jung, Dong-Hee Lee   +3 more
openaire   +1 more source

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

Advanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang, Chenhui Li, Dongjiao Wang, Qibin Wu, Zhen Zeng, Huiming Guo, Han Cheng, Songbi Chen, Hongxing Cao, Hongmei Cheng, Jianghui Xie, Youxiong Que   +11 more
wiley   +1 more source

Anti-Obesity Pharmacotherapy: Closing the Access Gap Through Local Manufacturing [PDF]

Journal of Advanced Biomedical Sciences
The global obesity epidemic, affecting approximately 890 million adults, has catalyzed substantial advances in pharmacological management. Contemporary anti-obesity medications, including GLP-1 receptor agonists, dual GLP-1/GIP agonists, lipase ...
Mojtaba Farjam, Babak Pezeshki, Narges Fereydouni   +2 more
doaj  

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

Essential, Yet Precarious, Mistreated, Sick and Medicalized: A Sequential Explanatory Mixed‐Methods Study on Homecare Aides in Spain

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Homecare aides (HCAs) are professional non‐family caregivers, who support dependent individuals to live at home with dignity; yet in Spain they remain understudied and vulnerable, often facing precarious working conditions. We aimed to characterize HCAs’ employment, living conditions, health, and exposure to workplace violence and ...
Albert Navarro‐Giné, Pedro Ferrer‐Rosende, Maria Feijoo‐Cid, Sergio Salas‐Nicás, Laura Esteve‐Matalí, Valeria Stuardo‐Ávila, María Isabel Fernández‐Cano   +6 more
wiley   +1 more source

Comparing clinical practice habits among obesity medicine physicians by patient, physician and clinic factors

Obesity Pillars
Background: While clinical practice habits vary by patient, physician and clinic factors in primary care, limited research has examined whether differences exist in obesity medicine.
Selvi Rajagopal, Edmond P. Wickham, III, Tirissa J. Reid, Dana R. Brittan, Judith Korner, Kimberly A. Gudzune   +5 more
doaj   +1 more source

Health‐Related Quality of Life, Everyday Executive Functioning, and Eating Behavior in Adults With Bardet–Biedl Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Bardet–Biedl syndrome (BBS) is a rare genetic condition with a broad phenotypic spectrum. Knowledge about quality of life, executive functioning, and eating behavior in adults with BBS remains limited. This study aimed to assess health‐related quality of life (HRQoL), everyday executive functioning, and eating behavior in adults with BBS and ...
Cecilie Fremstad Rustad, Charlotte von der Lippe, Hilde Nordgarden, Jeanette Ullmann Miller, Mina Susanne Weedon‐Fekjær, Ragnheidur Bragadottir, Solrun Sigurdardottir   +6 more
wiley   +1 more source

Can sibutramine alter systemic blood pressure in obese patients? Systematic review and meta-analysis

São Paulo Medical Journal
CONTEXT: Systemic arterial hypertension is part of the metabolic syndrome resulting from obesity. OBJECTIVE: To evaluate the effect of sibutramine on overweight and obese patients' blood pressure through a systematic review.
Hernani Pinto de Lemos Júnior, Álvaro Nagib Atallah, André Luis Alves de Lemos   +2 more
doaj   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Natural bioactive compounds and their mechanisms of action in the management of obesity: a narrative review

Frontiers in Nutrition
Obesity is a burning public health problem that affects both children and adult population all over the world. The incidence of obesity will increase in the coming years due to the urbanization of societies, which has led to unbalanced food intake and ...
Hassiba Benbaibeche, Ali Zineddine Boumehira, Ali Zineddine Boumehira, Naim Akhtar Khan   +3 more
doaj   +1 more source