Preparation and Evaluation of Liposomes and Niosomes Containing Total Ginsenosides for Anti-Photoaging Therapy. [PDF]
Ginsenosides are the principal bioactive compounds of ginseng. Total ginsenosides (GS) contain a variety of saponin monomers, which have potent anti-photoaging activity and improve the skin barrier function. To enhance the efficiency of GS transdermal absorption, GS liposomes (GSLs) and GS niosomes (GSNs) were formulated as delivery vehicles.
Jin Y +7 more
europepmc +4 more sources
Protective effect of the Rubus chingii Hu. fruit extract on ultraviolet B-induced photoaging via suppression of mitogen-activated protein kinases (MAPKs) in vitro [PDF]
Rubus chingii Hu. is an important traditional Chinese medicine with a beneficial effect on the kidney. Traditional Chinese medicine theory believes that supporting the kidney has a key role in anti-aging. To the best of our knowledge, the anti-photoaging
She Jie-Mei +4 more
doaj +1 more source
Molecular docking of lutein as anti-photoaging agent in silico
The accumulation of UV exposure resulted in the loss of skin elasticity, and the appearance of wrinkles on the skin is commonly known as photoaging. Matrix metalloproteinase-1 (MMP-1) is an enzyme that degrades type I and III fibrillar collagen. This study aims to determine the mechanism of MMP-1 inhibition by lutein, a carotenoid compound with high ...
I Gede Bayu Krisnayana +3 more
openaire +2 more sources
Anti-photoaging activities of Sorbaria kirilowii ethanol extract in UVB-damaged cells. [PDF]
Sorbaria kirilowii (Regel) Maxim, a plant found in China, Korea, Japan, and east of Europe, is a common herb used for traditional medicinal purposes. However, its ability to prevent photoaging has not been studied. In this study, we investigated the anti-photoaging functions of an ethanol extract (Sk-EE) of S.
Chen H +5 more
europepmc +4 more sources
Potential use of medicinal plants from Argentinean highland as agent anti‐photoaging [PDF]
AbstractBackgroundThe overexposure to sun ultraviolet (UV) radiation produce photoaging by effect of free radicals on lipid, protein, and nucleic acid or by direct activation of responsible enzymes of cleavage of extracellular matrix components (EMC).AimsTo develop new anti‐photoaging agents, the anti‐aging activity of four “jarillas” standardized ...
María Eugenia Orqueda +5 more
openaire +3 more sources
Photoaging is skin aging due to extrinsic factors. Photoaging occurs due to excessive degradation of collagen caused by excessive exposure to UV radiation.
I Gede Bayu Krisnayana +1 more
core +1 more source
Roles of oxidative stress in photoaging and the pathogenesis of systemic sclerosis [PDF]
我々の皮膚は常に外界からの様々な刺激にさらされている.その刺激の代表的なものとして太陽光線中の紫外線があげられる.紫外線は皮膚癌の発生の誘因となる他に,紫外線の曝露により皮膚には光老化と称される変化が生じてくる.光老化の特徴的な変化として皮膚表面のびまん性の色素沈着と深い皺があげられるが,その変化を特徴づけるものとして皮膚真皮におけるsolar elastosisと称される膠原線維・弾性線維の変化がある.この皮膚光老化には紫外線による酸化ストレスが深く関与していると考えられている.一方 ...
小川, 文秀, 佐藤, 伸一
core +1 more source
Design and Synthesis of Hydroxamate-Based Matrix Metalloproteinase-2 Inhibitors for Anti-Photoaging. [PDF]
Matrix metalloproteinases-2 (MMP-2) is crucial for collagen degradation at the dermal-epidermal junction, contributing to skin aging and photoaging. This study presents a series of hydroxamate-based inhibitors selectively targeting MMP-2. Through structure-activity relationship analysis, we systematically modified the N-arylsulfonyl group and amino ...
Lee JY +5 more
europepmc +3 more sources
Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline
Prolonged exposure to UV light can lead to photo-ageing of the skin. Therefore, the development and application of anti-photoaging drugs is urgent. In this study, we co-loaded apigenin (Apn) and doxycycline (Doc), a broad-spectrum inhibitor of matrix metalloproteinases (MMPs), into flexible liposomes to exert anti-photoaging effects by combating ...
Chang, Liu +9 more
openaire +2 more sources
Anti-Photoaging and Anti-Inflammatory Effects of Ginsenoside Rk3 During Exposure to UV Irradiation. [PDF]
Ginseng is a widely cultivated perennial plant in China and Korea. Ginsenoside Rk3 is one of the major active components of ginseng and is a promising candidate to regulate skin pigments and exert anti-photoaging effects on skin physiology. Ginsenoside Rk3 was mixed with a cream (G-Rk3 cream) and smeared on the skin of mice. Then, the mice were exposed
Wan S, Liu Y, Shi J, Fan D, Li B.
europepmc +5 more sources

