Results 31 to 40 of about 4,034 (217)
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Practical Realism: Against Standard Scientific Realism and Anti-Realism
In this paper, the elaboration of the concept of practical realist philosophy of science which began in the author's previous papers is continued.
Rein Vihalemm
doaj
Against the pragmatic justification for realism in economic methodology
In recent times, realism in economic methodology has increasingly gained importance. Uskali Mäki and Tony Lawson are the best-known realists within the discipline and even though their approaches are fundamentally different, both provide (among others ...
Simon Deichsel
doaj +1 more source
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
WITTGENSTEIN AGAINST THE REALISM/ANTI-REALISM DISTINCTION
In this Blue Book, Ludwig Wittgenstein puts forward an argument against the general realism/anti-realism distinction in metaphysics. If the argument is right, neither realism nor anti-realism concerning any putative element of reality is permissable.
George M. Strander
doaj
Essentialism, Metaphysical Realism, and the Errors of Conceptualism
Metaphysical realism is the view that most of the objects that populate the world exist independently of our thought and have their natures independently of how, if at all, we conceive of them.
E. Jonathan Lowe
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Moral Realism and Anti-Realism in Later Wittgenstein
By emphasis on cognitive aspect of moral realism, this article surveys various divisions in moral realism and anti-realism and, regarding later Wittgenstein's courses, it explores his views about this matter.
A Sabramiz, S Dabagh
doaj
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
American metaphysics of race In the 1990s, a debate about the race began in the United States, in which many philosophers are involved. In philosophy, this debate has become known as the metaphysics of race.
Mieczysław Jagłowski
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