Results 31 to 40 of about 2,078,454 (291)
Empirical realism and the legitimacy of ontology: A dialogue [PDF]
, 2015 The purpose of this dialogue between an ‘empirical realist’ and a ‘traditional ontologist’ is to clarify and evaluate the presuppositions of the kind of antiontological position exemplified by empirical realism.
McWherter, Dustin
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
What Kind of Non-Realism is Fictionalism?
Ergo, An Open Access Journal of PhilosophyFictionalists about a kind of disputed entity aim to give a face-value interpretation of our discourse about those entities without affirming their existence.
Nathaniel Gan
doaj +2 more sources
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Can van Fraassen's anti-realism give an account of novel predictions of unexpected phenomena? [PDF]
, 2011 In this paper it will be addressed the possibility of an account of novel predictions of unexpected phenomena by physical theories within van Fraassen's anti-realism.
Bacelar Valente, Mario
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The Significance of Being Ethical: An essay on the case for moral realism and theism
Scientia et Fides, 2016 William Irwin defends a form of moral anti-realism, according to which there are no objective moral facts. He contends that moral realism is objectionable because of its being more complex or not as simple as anti-realism; moral realism is in conflict ...
Charles Taliaferro
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The Argument from Underconsideration and Relative Realism [PDF]
, 2013 In this paper, through a critical examination of Wray’s version of the argument from underconsideration against scientific realism, I articulate a modest version of scientific realism.
Mizrahi, Moti
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