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Practical Realism: Against Standard Scientific Realism and Anti-Realism
In this paper, the elaboration of the concept of practical realist philosophy of science which began in the author's previous papers is continued.
Rein Vihalemm
doaj
Essentialism, Metaphysical Realism, and the Errors of Conceptualism
Metaphysical realism is the view that most of the objects that populate the world exist independently of our thought and have their natures independently of how, if at all, we conceive of them.
E. Jonathan Lowe
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Experimental Realism Defended: How Inference to the Most Likely Cause Might Be Sound [PDF]
On a purely epistemic understanding of experimental realism, manipulation affords a particularly robust kind of causal warrant, which is – like any other warrant – defeasible.
Suárez, Mauricio, Mauricio Suárez
core
Scientific Realism and High-Energy Physics
The article discusses the implications of high-energy physics for the scientific realism debate. After a brief introduction to high-energy physics, the anti-realist import of the erosion of intuition-based concepts in the context of high-energy physics ...
Dawid, Richard,, Richard Dawid
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Against the pragmatic justification for realism in economic methodology
In recent times, realism in economic methodology has increasingly gained importance. Uskali Mäki and Tony Lawson are the best-known realists within the discipline and even though their approaches are fundamentally different, both provide (among others ...
Simon Deichsel
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Why the Ultimate Argument for Scientific Realism Ultimately Fails [PDF]
In this paper, I argue that the ultimate argument for Scientific Realism, also known as the No-Miracles Argument (NMA), ultimately fails as an abductive defence of Epistemic Scientific Realism (ESR), where (ESR) is the thesis that successful theories of ...
Mizrahi, Moti
core
Moral Realism and Anti-Realism in Later Wittgenstein
By emphasis on cognitive aspect of moral realism, this article surveys various divisions in moral realism and anti-realism and, regarding later Wittgenstein's courses, it explores his views about this matter.
A Sabramiz, S Dabagh
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

