Results 41 to 50 of about 12,098 (310)

Can the empirical sciences contribute to the moral realism/anti-realism debate? [PDF]

open access: yes, 2018
An increasing number of moral realists and anti-realists have recently attempted to support their views by appeal to science. Arguments of this kind are typically criticized on the object-level.
Pölzler, Thomas
core  

Essentialism, Metaphysical Realism, and the Errors of Conceptualism

open access: yesPhilosophia Scientiæ, 2008
Metaphysical realism is the view that most of the objects that populate the world exist independently of our thought and have their natures independently of how, if at all, we conceive of them.
E. Jonathan Lowe
doaj   +1 more source

An Interpretation of the Deep Disagreement between Plato and Protagoras from the Perspective of Contemporary Meta-Ethics and Political Epistemology

open access: yesPhilosophies, 2023
Since the early 20th century, two new disciplines emerged in the tradition of analytic philosophy: meta-ethics and political epistemology. Nevertheless, debates on such questions go back to the ancient Greeks and, in particular, to the debates between ...
Manuel Knoll
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Realismo/Anti-Realismo [PDF]

open access: yes, 2014
State of the art paper on the topic realism/anti-realism. The first part of the paper elucidates the notions of existence and independence of the metaphysical characterization of the realism/anti-realism dispute.
Castro, Eduardo
core   +1 more source

Spinoza on Composition, Monism, and Beings of Reason [PDF]

open access: yes, 2020
In this paper, I argue that Spinoza holds a perspectivalist view of mereological composition, a form of anti-realism. The paper has two parts: In the first half of the paper, I introduce interpretive puzzles for the standard realist reading of Spinoza’s ...
Mátyási, Róbert
core  

Against the pragmatic justification for realism in economic methodology

open access: yesErasmus Journal for Philosophy and Economics, 2011
In recent times, realism in economic methodology has increasingly gained importance. Uskali Mäki and Tony Lawson are the best-known realists within the discipline and even though their approaches are fundamentally different, both provide (among others ...
Simon Deichsel
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Further problems with projectivism [PDF]

open access: yes, 2016
From David Hume onwards, many philosophers have argued that moral thinking is characterized by a tendency to “project” our own mental states onto the world.
Pölzler, Thomas
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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