Results 51 to 60 of about 12,098 (310)

Fitch's Paradox and the Problem of Shared Content [PDF]

open access: yes, 2006
According to the “paradox of knowability”, the moderate thesis that all truths are knowable – ... – implies the seemingly preposterous claim that all truths are actually known – ... –, i.e. that we are omniscient.
Sander, Thorsten
core  

Practical Realism: Against Standard Scientific Realism and Anti-Realism

open access: yesStudia Philosophica Estonica, 2012
In this paper, the elaboration of the concept of practical realist philosophy of science which began in the author's previous papers is continued.
Rein Vihalemm
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Cognitive science and epistemic openness [PDF]

open access: yes, 2005
Recent findings in cognitive science suggest that the epistemic subject is more complex and epistemically porous than is generally pictured. Human knowers are open to the world via multiple channels, each operating for particular purposes and according ...
Anderson, Dr. Michael L.
core  

Queering the Family: Fantasy and the performance of sexuality and gay relations in French cinema 1995-2000 [PDF]

open access: yes, 2002
This paper looks in detail at the representation of sexuality in the family in three films of the mid to late 1990s, Balasko’s Gazon maudit, Berliner’s Ma Vie en rose, and Giusti’s Pourquoi pas moi?
Ince, Kate
core   +1 more source

WITTGENSTEIN AGAINST THE REALISM/ANTI-REALISM DISTINCTION

open access: yesDaimon, 1990
In this Blue Book, Ludwig Wittgenstein puts forward an argument against the general realism/anti-realism distinction in metaphysics. If the argument is right, neither realism nor anti-realism concerning any putative element of reality is permissable.
George M. Strander
doaj  

Normative Reasons, Epistemic Autonomy, and Accountability to God

open access: yesReligions, 2023
According to many, human autonomy is necessary for moral action and yet incompatible with being morally accountable to God’s divine commands. By issuing commands that ground normative facts, God demands our accountability without understanding our ...
Brandon Rickabaugh
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Moral Realism and Anti-Realism in Later Wittgenstein

open access: yesMetaphysics, 2011
By emphasis on cognitive aspect of moral realism, this article surveys various divisions in moral realism and anti-realism and, regarding later Wittgenstein's courses, it explores his views about this matter.
A Sabramiz, S Dabagh
doaj  

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