Results 111 to 120 of about 129,223 (217)

Defining and Predicting HIV Immunological Non-Response: A Multi-Definition Analysis from an Indonesian Cohort

Viruses
Immunological non-response (INR) to antiretroviral therapy (ART) is a critical concern for PLHIV, characterized by inadequate CD4+ T-cell recovery despite virological suppression.
Brian Eka Rachman, Yehuda Tri Nugroho Supranoto, Soraya Isfandiary Iskandar, Tri Pudy Asmarawati, Siti Qamariyah Khairunisa, Muhammad Vitanata Arfijanto, Usman Hadi, Muhammad Miftahussurur, Nasronudin Nasronudin, Masanori Kameoka, Retno Pudji Rahayu, Afif Nurul Hidayati   +11 more
doaj   +1 more source

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites.

PLoS ONE, 2015
Cancer cells have a high iron requirement and many experimental studies, as well as clinical trials, have demonstrated that iron chelators are potential anti-cancer agents.
Eliška Potůčková, Jaroslav Roh, Miloslav Macháček, Sumit Sahni, Ján Stariat, Vít Šesták, Hana Jansová, Pavlína Hašková, Anna Jirkovská, Kateřina Vávrová, Petra Kovaříková, Danuta S Kalinowski, Des R Richardson, Des R Richardson, Tomáš Šimůnek   +14 more
doaj   +1 more source

Deciphering the full spectrum of Castleman diseases based on a cohort of 700 patients in a western country

British Journal of Haematology, Volume 208, Issue 6, Page 2036-2046, June 2026.
The spectrum of Castleman diseases has expanded over the past three decades. The phenotype of the diseases varies not only among the three major types but also according to the patient ancestry. Summary Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time.
Eric Oksenhendler, Marion Malphettes, Véronique Meignin, David Boutboul, Lionel Galicier   +4 more
wiley   +1 more source

Synthesis, Characterisation, DFT and Docking Analysis of 3-Methyl-2,6-bis(3-methylphenyl)piperidin-4-one (MBMP) as Anti-Retroviral Therapeutic Agent

Asian Journal of Chemistry
RNA is vital in HIV gene expression and replication. Despite antiretroviral therapy (ART) advancements, the high mutation of HIV rate remains challenging. In this work, the synthesis, quantum chemical analysis and molecular docking of 3-methyl-2,6-bis(3-methyl-phenyl)piperidin-4-one (MBMP) were carried out to evaluate its potential as an anti ...
J. Gershom Stuart, J. Winfred Jebaraj
openaire   +1 more source

Hierarchical Citizenship and Racialised Discretion: Police and Consular Officers’ Handling of Capital Cases in Malaysia

The Howard Journal of Crime and Justice, Volume 65, Issue 2, Page 226-236, June 2026.
ABSTRACT This article examines the death penalty in Malaysia, where foreign nationals have historically been sentenced to death at a disproportionately high rate. The international community has recognised that foreign defendants are disadvantaged in alien criminal justice systems and made efforts to address this through the United Nation's Vienna ...
Carolyn Hoyle, Lucy Harry
wiley   +1 more source

Cyclopentenone prostaglandins as anti-inflammatory agents: a novel therapeutic strategy.

, 2003
Cyclopentenone prostaglandins (cyPG) are naturally occurring derivatives of prostaglandin E1, E2, and D2 containing an α,β-unsaturated carbonyl group in the cyclopentane ring structure (cyclopentenone).
IANARO, ANGELA, MAFFIA P, IALENTI, ARMANDO, DI ROSA M, Rosa, M., Maffia, P., Ianaro, A., Ialenti, A.   +7 more
core   +1 more source

Terapia antirretroviral altamente eficaz para infecção pelo vírus da imunodeficiência humana aumenta a rigidez aórtica

Arquivos Brasileiros de Cardiologia
FUNDAMENTO: Sabe-se que a terapia antirretroviral altamente potente para Aids reconhecida aumenta o risco cardiovascular, mas os efeitos dos agentes antirretrovirais de acordo com o gênero ainda são desconhecidos.
Margareth Eira, Isabela M. Bensenor, Egidio Lima Dorea, Roberto Sá Cunha, José Geraldo Mill, Paulo A. Lotufo   +5 more
doaj  

[Modern methods of detection of HIV resistance to the action of anti-retroviral agents].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 2002
The work deals with the molecular mechanisms of the development of resistance of HIV to modern preparations for treatment of HIV infection and AIDS: inhibitors of reverse transcriptase and protease. The principles and concrete schemes of the use of modern methods of geno- and phenotypic resistance determination of HIV are described in detail.
openaire   +1 more source

Anti-Tumor Mechanisms of Novel 3-(4-Substituted Benzyl)-5-Isopropil-5- Phenylhydantoin Derivatives in Human Colon Cancer Cell Line

, 2019
Background: Hydantoin and its newly synthesized derivatives have recently become a focus of interest due to their numerous biological activities and newly emerging beneficial effects in different pathological conditions, including cancer.
Matić, Miloš, Ušćumlić, Gordana, Obradović, Ana, Božić, Bojan, Vuković, Nenad, Ognjanović, Branka, Vukić, Milena, Božić Nedeljković, Biljana, Djurdjevic, Predrag   +8 more
core   +1 more source

Interaction between pharmaceutical companies and physicians who prescribe antiretroviral drugs for treating AIDS

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Given that Brazil has a universal public policy for supplying medications to treat HIV and AIDS, the aim here was to describe the forms of relationship between physicians and the pharmaceutical companies that produce ...
Mario Cesar Scheffer
doaj   +1 more source