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Polycyclic aromatic compounds (Print), 2022
Sulfonamide-based carboxamide drugs have multiple active sites that confers them with a variety of chemical and pharmacological activities. The combination of structural functionalities has been established to be vital in the drug discovery process.
Fredrick C. Asogwa +10 more
semanticscholar +1 more source
Sulfonamide-based carboxamide drugs have multiple active sites that confers them with a variety of chemical and pharmacological activities. The combination of structural functionalities has been established to be vital in the drug discovery process.
Fredrick C. Asogwa +10 more
semanticscholar +1 more source
Nigerian Journal of Parasitology
African Animal Trypanosomiasis is a disease of major economic and public health importance, especially with the current setback in the treatment of cases using synthetic anti-trypanosomal agents.
A. Ismail +5 more
semanticscholar +1 more source
African Animal Trypanosomiasis is a disease of major economic and public health importance, especially with the current setback in the treatment of cases using synthetic anti-trypanosomal agents.
A. Ismail +5 more
semanticscholar +1 more source
Organic and biomolecular chemistry, 2014
An improved, Weinreb amide-based, synthesis of anti-trypanosomal lysine-containing vinyl sulfones is described incorporating, as a feature, diversity at the ε-lysine amino group.
W. Doherty +6 more
semanticscholar +1 more source
An improved, Weinreb amide-based, synthesis of anti-trypanosomal lysine-containing vinyl sulfones is described incorporating, as a feature, diversity at the ε-lysine amino group.
W. Doherty +6 more
semanticscholar +1 more source
Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones.
Planta Medica, 2002The anti-trypanosomal activity of six sesquiterpene lactones (helenalin, mexicanin I, 11alpha,13-dihydrohelenalin acetate, chamissonolide, ivalin and isoalantolactone) against the African Trypanosoma brucei rhodesiense and American T.
T. Schmidt +3 more
semanticscholar +1 more source
, 2016
A major problem besetting the chemotherapy of African Trypanosomiasis is parasite resistance to the few available drugs, and a known strategy is to use combination of drugs to overcome parasite drug resistance.
A. Abubakar +5 more
semanticscholar +1 more source
A major problem besetting the chemotherapy of African Trypanosomiasis is parasite resistance to the few available drugs, and a known strategy is to use combination of drugs to overcome parasite drug resistance.
A. Abubakar +5 more
semanticscholar +1 more source