Results 161 to 170 of about 7,382,706 (304)

A Super-Resolution Approach for Astrocyte-Specific Molecular Imaging Reveals the Nanoscale Distribution of Monoacylglycerol Lipase, the Metabolic Node Between Endocannabinoid and Prostaglandin Signaling. [PDF]

Glia
Zöldi M, Katona I.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Development and qualification of an enzyme-linked immunosorbent assay to detect human serum immunoglobulin G reactive to multiple lineages of Lassa virus nucleoprotein. [PDF]

PLoS One
Yun H, Sigei F, Appiah NYA, Quaye CNO, Yankey CAB, Kyei-Baafour E, Hayes P, Marini A, Bailer RT, Zaric M, Kusi KA.   +10 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

A Next-Generation ELISA for the Detection of Anti-(Para)Nodal Antibodies in Autoimmune Nodopathy and COVID-19 Vaccinated Individuals. [PDF]

J Peripher Nerv Syst
Appeltshauser L, Ruprecht C, Reusch J, Mees J, Glenewinkel H, Sommer C, Krone M, Wagenhäuser I, Doppler K, Petri N.   +9 more
europepmc   +1 more source

Northern Territory Anti-Discrimination Commission annual report 2000-2001

, 2001
Date:2001This publication contains many links to external sites. These external sites may no longer be active.Made available by via the Publications (Legal Deposit) Act 2004 (NT)

core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A Circulating GPNMB-Based Multimodal Model Integrates Tumor-Immune Crosstalk to Predict Immunotherapy Response in Esophageal Cancer. [PDF]

Cancer Discov
Zhu L, Wang X, Cheng G, Lai Y, Lan L, Dong Z, You Z, Chen X, He Z, Xiao X, Zhu L, Liu R, Zhang L, Zhang S, Lin D, Wu C, Chang J.   +16 more
europepmc   +1 more source

Northern Territory Anti-Discrimination Commission annual report 2012-2013

, 2013
Date:2013This publication contains many links to external sites. These external sites may no longer be active.Made available by via the Publications (Legal Deposit) Act 2004 (NT)

core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source