Results 91 to 100 of about 532,092 (302)

Influence of hypoxia and neoangiogenesis on the growth of pancreatic cancer

open access: yesMolecular Cancer, 2003
As with other solid tumors, the growth and metastasis of pancreatic cancer is critically dependent on tumor angiogenesis. A major stimulus for a tumor's recruitment of additional blood vessels is cellular hypoxia, a condition which is especially ...
Reber Howard A   +3 more
doaj   +1 more source

Involvement of pro-inflammatory cytokines and growth factors in the pathogenesis of Dupuytren's contracture: a novel target for a possible future therapeutic strategy? [PDF]

open access: yes, 2015
Dupuytren's contracture (DC) is a benign fibro-proliferative disease of the hand causing fibrotic nodules and fascial cords which determine debilitating contracture and deformities of fingers and hands.
Alberto Signore   +11 more
core   +1 more source

The temporal trends and short‐ and long‐term mortality of people with acute myocardial infarction and rheumatoid arthritis: a nationwide cohort study

open access: yesArthritis Care &Research, Accepted Article.
Aims We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analysed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalised with AMI between 2005 and 2019 from the MINAP registry, linked ...
Megan Butler   +8 more
wiley   +1 more source

Clinical utilization of anti-vascular endothelial growth-factor agents and patient monitoring in retinal vein occlusion and diabetic macular edema

open access: yesClinical Ophthalmology, 2014
Szilárd Kiss,1 Ying Liu,2 Joseph Brown,3 Nancy M Holekamp,4,5 Arghavan Almony,6 Joanna Campbell,2 Jonathan W Kowalski2 1Weill Cornell Medical College, New York, NY; 2Allergan, Inc., Irvine, CA; 3IMS Health, Woodland Hills, CA; 4Pepose Vision ...
Kiss S   +6 more
doaj  

Diabetic macular edema: it is more than just VEGF [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Diabetic macular edema is a serious visual complication of diabetic retinopathy. This article reviews the history of previous and current therapies, including laser therapy, anti-vascular endothelial growth factor agents, and corticosteroids, that have ...
Michael A. Singer   +4 more
doaj   +1 more source

Anti-vascular endothelial growth factor for unilateral acute idiopathic maculopathy

open access: yesEuropean Journal of Ophthalmology, 2017
Purpose: To describe a case of unilateral acute idiopathic maculopathy (UAIM) response to intravitreal therapy with aflibercept (Eylea). Methods: Retrospective case report. Results: A 36-year-old woman with sudden visual impairment and central scotoma was found to have a UAIM in her left eye.
Mylonas, G.   +5 more
openaire   +3 more sources

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

open access: yesArthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Effects of anti-vascular endothelial growth factor monoclonal antibody (bevacizumab) on lens epithelial cells

open access: yesClinical Ophthalmology, 2016
Jong Hwa Jun,1 Wern-Joo Sohn,2 Youngkyun Lee,2 Jae-Young Kim21Department of Ophthalmology, School of Medicine, Dongsan Medical Center, Keimyung University, 2Department of Oral Biochemistry, School of Dentistry, IHBR, Kyungpook National University, Daegu,
Jun JH, Sohn WJ, Lee Y, Kim JY
doaj  

Epiretinal Membrane – What does It Change in Anti-vascular Endothelial Growth Factor Therapy Injection (anti-VEGF)?

open access: yesOkulistyka
Epiretinal membrane is a type of fibrous proliferation on the retinal surface in the macular region. Its most common symptoms include metamorphopsia, micropsia, macropsia, and reduced visual acuity. When these symptoms are present, patients are typically
Paulina Glasner   +2 more
doaj   +1 more source

Positive and negative regulation of angiogenesis by soluble vascular endothelial growth factor receptor-1 [PDF]

open access: yes, 2018
Vascular endothelial growth factor receptor (VEGFR)-1 exists in different forms, derived from alternative splicing of the same gene. In addition to the transmembrane form, endothelial cells produce a soluble VEGFR-1 (sVEGFR-1) isoform, whereas non ...
Carbo, Miriam   +2 more
core   +2 more sources

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