Results 101 to 110 of about 11,095,042 (285)

Gene expression analysis in human breast cancer associated blood vessels [PDF]

open access: yes, 2012
Angiogenesis is essential for solid tumour growth, whilst the molecular profiles of tumour blood vessels have been reported to be different between cancer types.
John M J Herbert   +53 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Metabolomics of Green-Tea Catechins on Vascular-Endothelial-Growth-Factor-Stimulated Human-Endothelial-Cell Survival

open access: yes, 2018
Neovascularization causes serious oculopathy related to upregulation of vascular-endothelial-growth factor (VEGF) causing new capillary growth via endothelial cells. Green-tea-extract (GTE) constituents possess antiangiogenesis properties.
Vishal Jhanji   +13 more
core   +1 more source

IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]

open access: yes, 2012
Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Steffen Kunzmann   +14 more
core   +2 more sources

Self‐Feeding Living Materials Enabled by Cell Responsive Glycogen Nanoparticles as Metabolic Batteries

open access: yesAdvanced Materials, EarlyView.
Glycogen is introduced as a metabolic battery that offers local and cell‐triggered release of glucose. Glycogen can be stably encapsulated into hydrogel (Dex‐TA) microcapsules that allow for diffusion of glycogen‐degrading enzymes and nutrients.
Melvin Gurian   +8 more
wiley   +1 more source

Mechanisms of vascular morphogenesis and stabilization by VEGF dose [PDF]

open access: yes, 2014
VEGF is the master regulator of angiogenesis and the most investigated factor in therapeutic angiogenesis approaches to induce the growth of new vessels that could restore oxygen and nutrients supply in tissues affected by ischemia.
Groppa, Elena
core   +1 more source

Endothelial cell impact on smooth muscle cell properties: role of hemodynamic forces [PDF]

open access: yes, 2009
The vascular endothelium is a dynamic cell monolayer located at the interface of the vessel wall and bloodstream, where it regulates the physiological effects of humoral and hemodynamic stimuli on vessel tone and remodelling.
Killeen, Maria T.
core   +2 more sources

Diabetic macular edema: it is more than just VEGF [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Diabetic macular edema is a serious visual complication of diabetic retinopathy. This article reviews the history of previous and current therapies, including laser therapy, anti-vascular endothelial growth factor agents, and corticosteroids, that have ...
Michael A. Singer   +4 more
doaj   +1 more source

Intravitreal Anti–Vascular Endothelial Growth Factor in Retinopathy of Prematurity [PDF]

open access: yesAsia-Pacific Journal of Ophthalmology, 2014
Retinopathy of prematurity (ROP) is a disorder of the developing retina, affecting premature infants of low birth weight and remains one of the leading causes of childhood blindness in the United States.1 As advanced neonatal intensive care services become more prevalent and high risk neonates survive globally, ROP has become a significant cause of ...
openaire   +2 more sources

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

open access: yesAdvanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris   +11 more
wiley   +1 more source

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